Question

how hypoxia related to seizures

Answer 1

Hypoxia of the brain is closely related to the seizure. Brain cells are very sensitive to oxygen, without oxygen they can die within 5 minutes.

If there is a lack of oxygen supply to the brain due to some reason, it can cause electrical disturbances of brain which leads to various types of seizures(An electrical storm in the brain). Seizures also can accelerate brain damage.

In another aspect,

Seizures also can cause hypoxia of the brain. A repetitive seizure can cause serious brain damage,

Oxygen therapy during the seizure and after the seizure can help to reduce hypoxic brain damage.