arrange the order of events for the internalization of LDL particles into cells:
1) A combination of cholesterol and apolipoprotein binds to LDL
receptors and becomes internalized as endocytotic vesicles.
2) The environment of the endosome becomes acidic, which causes the
LDL to dissociate from its receptor; additionally, the endosome
fuses with a lysosome.
3) Several endocytotic vesicles fuse to form an endosome.
4) The LDL particle is degraded by the lysosome.
5) LDL receptors migrate to the cell surface and cluster in
clathrin-coated pits.
5) LDL receptors migrate to the cell surface and cluster in clathrin-coated pits.
1) A combination of cholesterol and apolipoprotein binds to LDL receptors and becomes internalized as endocytotic vesicles.
3) Several endocytotic vesicles fuse to form an endosome.
2) The environment of the endosome becomes acidic, which causes the LDL to dissociate from its receptor; additionally, the endosome fuses with a lysosome.
4) The LDL particle is degraded by the lysosome.
arrange the order of events for the internalization of LDL particles into cells: 1) A combination...
Question 19 Consider the endocytosis of LDL particles by human skin cells. Of the event listed, which one takes place first is the earliest event, or those listedi? - Uncoating of clathrin from vesicle -Fusion of late endosome to lysosome - Dissociation of LDL. from LDL receptor - Fusion of endocytotic vesicle to early endosome Fusion of endocytoti vesicle to early endosome Uncoating of clathrin from veside Fusion of late endosome to lysosome Dissociation of LDL from LDL receptor