The inherited function of the gene is given by the original gene. The duplicate genes are basically give up the elements that are free to develop new functions and are called neo-functionalization. Thorough examination of genomes and population genetic thoughts has guided to an improved knowledge of the alternative fates of new gene duplicates. The three alternative fates of a new gene duplicate are as follows:
i. In the coding region of any duplicate, an inactivating mutation may occur, which was termed as pseudogene and will usually be nonexistent to natural selection. Therefore, it will build up more mutations and develop by random genetic drift, whereas the natural selection will retain the functional paralog (any pair of genes that obtain from the similar ancestral gene).
ii. By altering the action of one encoded protein or the control of one duplicate gene may cause mutations. These alleles can subsequently become subject to positive selection and obtain a new function.
iii. In some situations where the ancestral gene has one extra function or one extra regulatory element, such as for most toolkit genes, a third potential product is that initial mutations inactivate or change one regulatory element in every duplicate gene. The function of the original gene is then separated among the duplicates, which balance each other. In turn to maintain the inherited function, natural selection will preserve the reliability of both gene coding regions. Loci that aim for the means of duplication and mutation that generate complementary paralogs are believed to be sub-functionalized.