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Solutions For An Introduction to Genetic Analysis Chapter 20 Problem 25P

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Solution 1

A species with polymorphic sites let non-synonymous = a and synonymous = b.

For polymorphic sites among the species, let non-synonymous = c and synonymous = d.

If the difference is due to neutral evolution, then a/b = c/d.

Whereas, if the variation is due to selection, then a/b < c/d.

But, in this case a/b = 20/50 > c/d = 2/18, that matches neither expectations as the ratio of non-synonymous to synonymous polymorphisms (a/b) is comparatively high and the gene being examined can encode a protein tolerant of relatively less species variations. This may possibly suggest that speciation was a new occurrence. Hence, new polymorphisms have been permanent in one species that are not alternates in the further.

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