Partial rate factors may be used to estimate product distributions in disubstituted benzen...

Partial rate factors may be used to estimate product distributions in disubstituted benzene derivatives. The reactivity of a particular position in obromotoluene, for example, is given by the product of the partial rate factors for the corresponding position in toluene and bromobenzene. On the basis of the partial rate factor data given here for Friedel- Crafts acylation, predict the major product of the reaction of obromotoluene with acetyl chloridc and aluminum chloride.