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Solutions For An Introduction to Genetic Analysis Chapter 1 Problem 13P

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Solution 1

DNA (deoxyribonucleic acid) acts as the genetic material in most of the living organisms. This is the hereditary vehicle carrying the genetic information from one generation to the other.

It is a long polymeric molecule made up of four different deoxyribonucleotides, namely deoxyadenosine (dAMP), deoxyguanosine (dGMP), deoxythymidine (dTMP) and deoxycytidine (dCTP). For example, in humans, approximately three billion base pairs are present.

Based on the Chargaff’s rule, Adenine (A) pairs with thymine (T) with two hydrogen bonds and Guanine pairs (G) with cytosine (C) with three hydrogen bonds, and vice versa.

The adjoined picture shows hydrogen bonding between complimentary nucleotides.

C:\Users\rajesh.r\Desktop\hydrogen bonds.jpg

The average enthalpy for the hydrogen bond is about. Thus, to break down a base pair require and base pair require

If DNA has more amount of content than content, it requires more amount of energy (heat) to melt it down, and vice versa.

For example, consider two DNA molecules; first one has 100 base pairs and the second one has 50 base pairs in length. Both have and content. So, the first molecule needs and second molecule needs

Thus, the DNA with more length require high amount of heat energy than DNA with less length.

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