Question

Spid deri 7. What is the order of DECREASING reactivity toward nucleophilic acyl substitution for these carboxylic acid derivatives (most reactive first)? 9. Using your knowledge of organic chemistry, what is the order from most reactive to least reactive of these esters toward a nucleophile? och la NHCH I NHCH 1 2 (a) II, IV, III, I (b) I, II, III, IV (a) 1 > 2 > 3 (b) 3 >1 > 2 (c) 2 > 3 > 1 >2 > 1 (e) 1 > 3 > 2 w ν v (c) III, IV, 1, 11 (d) IV, I, II, III (e) II, IV, I, III 10. Select the product of the following reaction. NON 1. LAH 2. Ho (quench) 8. The reaction (a general example is shown below) that is typical of carboxylic acids, esters, acid chlorides, anhydrides and amides is called: NH2 (a) Nucleophilic Substitution Bimolecular (b) Nucleophilic Addition (c) Electrophilic Substitution (d) Nucleophilic Acyl Substitution (e) Electrophilc Addition NH2 no reaction will occur

Answer 1

identify the carboxylic acid derivatives reactivity and then write the oreder

carbonyl compounds undergoes the nucleophilic addition reactions only

due to the elctronegative elements present on ester the reactivity increses

nitriles undergoes the reduction and forms the amine

o lari > Slotta > & WHchle Ester Amide chande (more Reacties Paco order a =) © I , IN Auguser I, II رهه مه و Mue ها - مه & Nucleophtic. Addition a because the Compound has the czo unsettarted - center - 10) - o mac cries Hichochhe Auswor@ 17372 meN LAH , n Nha Nitrile - Amine Reduction H20 Nitrile Amine