Question

Lipid lowering agents

1. Hyperlipidemia is seen in all age groups. What are the drugs of choice for the various age groups, gender and racial groups?

2. Why is timing of statin administration important? What other patient education information would you include to a patient beginning treatment of statin drugs?

Answer 1

Typerlipidemia aše inhibitor Tavastatin ) -(18-55%), triglycerides Cases HOL (5-15%) I the synthesis of e liver by the enzyme option inhibitor Treatment of Hyperlip! IX HMG CoA reductase inh Levastatin / Pravastatin It decreases LDL (18-551 (7-30%), increases HOLES work by inhibiting the a cholesterol in the liver by HMG CoA reductase. 11) Cholesterol absorption in hibit (Ezetimibe) (works by reducing the amoun cholesterol that body absorbs fro m Nicotinic Acid (Nitamin B3) It works by reducing the amount of bad cholesterol & triglycerides made by the liver. in Fibric Acids (Gemfibrozil, Fenofibrcute) V Bile acid (cholestyramine) it ↑ HOL, & LDL & no change in triglycerides y the amount of Podly absorbs from fat)

Statins are a classe lower the levels of artery clogy (bad) cholesterol in bloods 8tatin should be given evening time because cho biosynthesized in the early nee hours. It has shorter halt The best time to take stations on the specific drug. It shoula taken once in a day. 2 class of drugs that tery clogging LDL un bloodstream. e given in the ecaise cholesterol is early morning is shorter half life. le to take statins depends → Patient teaching: It should be taken with meal for better work. Store all the medicines in a cool, dry place , keep them away from children. Follow healthy diet that indudes. eating less hat in diet other ways are getting regular exercise, managing stress, quitting "smoking