Which criteria are necessary for establishing causation? Discuss these criteria in the context of smoking and lung cancer.
Answer: The English statistician Sir Austin Bradford Hill in 1965, proposed a set of nine criteria to provide epidemiologic evidence relationship between a presumed cause and an observed effect. It is necessary for establishing causation because there should be at least presumed caused must be known. For the better treatment, there must be a criterion which includes the possibilities of the disease occurs.
The smoking and lung cancer is correlated, as smoking includes the consumption of tobacco along with many other harmful substances. the carbon causes collection of tar in the lungs which kills the respiratory cells and causes slow death of the lungs. These dead cells accumulate and form the tumor with the bacterial infection, hence causes lung cancer. So here the causation established that those people who are chain smoker are very prone to lung cancer and respiratory tract diseases.
Which criteria are necessary for establishing causation? Discuss these criteria in the context of smoking and...
Recall the casual criteria presented by Sir Austin Bradford Hill in 1965: Casual Criteria Discuss the criteria in the context of 1) smoking and lung cancer and 2) sleep and weight gain/loss.
1. Suppose that the causal relationship between smoking and lung cancer is as follows. Whether or not you get lung cancer depends on whether you have a particular genetic makeup: if you do, then smoking will cause you to get lung cancer and if you don't then smoking will not give you lung cancer. Furthermore, smoking is a necessary condition for lung cancer. Under these hypotheses, the decision whether or not to smoke looks as follows: state -genetic predisposition s:...
discuss the three necessary conditions for causation. What is a correlation? What is the difference between a positive and negative correlation? Give an example of each. What is a correlation coefficient and what would be a perfect one numerically?
Which of Hill’s Criteria of Causation stemmed from Koch’s Postulates and was important in judging the causal relationship between an infectious agent and a disease, but is somewhat inadequate for assessing noninfectious chronic diseases? Strength of the association Temporality Specificity Biologic gradient Analogy
Lung Cancer & Smoking Case Study A causal relationship between cigarette smoking and lung cancer was first suspected in the 1920s on the basis of clinical observations. To test this apparent association, numerous epidemiologic studies were undertaken between 1930 and 1960. Two studies were conducted by Richard Doll and Austin Bradford Hill in Great Britain. The first was a case-control study begun in 1947 comparing the smoking habits of lung cancer patients with the smoking habits of other patients. The...
Question 35 Which of Hill's Criteria of Causation is being described in the following scenario: Evidence has shown that Down's Syndrome occurs when there are three chromosomes on the 21st set and no other known exposure appears to be associated with the occurrence of Down's Syndrome Strength of the association Consistency of the association Specificity TemporalityThe role of chance may affect a statistical association because of: Loss to follow-up Selection bias Random variation Misclassification bias None of the answers listed
Lung Cancer & Smoking Case Study A causal relationship between cigarette smoking and lung cancer was first suspected in the 1920s on the basis of clinical observations. To test this apparent association, numerous epidemiologic studies were undertaken between 1930 and 1960. Two studies were conducted by Richard Doll and Austin Bradford Hill in Great Britain The first was a case-control study begun in 1947 comparing the smoking habits of lung cancer patients with the smoking habits of other patients. The...
In a population-based cohort study, an entire community was interviewed regarding smoking habits and then followed for one year. Upon ascertainment of all lung cancer deaths, the investigator obtained the following data: [which may or may not be in the standard table to calculate your answers – beware!]. Number of individuals Incidence of Lung cancer deaths Smokers 24,500 15 Non-smokers 10,500 2 Calculate the RR of smoking and lung cancer death. Interpret your results in a sentence. ...
16. In the U.S. smoking rates among women have begun to decline. However, lung cancer mortalities are still increasing. Which one of the following could be used to help explain these trends? a. Cigarette smoking is increasing among the YOUTH in the U.S. b. a 20-year lag period between trends in cigarette smoking and trends in lung cancer mortality obscure the effects of declining smoking rates. c. FAB associated metabolism rates increases the negative effects of smoking. d. none of...
Consider and discuss the learning needs of the following clients: An individual who has recently been diagnosed with lung cancer. A family caring for an elderly individual with Alzheimer’s disease. A community in which adolescent cigarette smoking is on the rise.