Ans17) Flavin-dependent monooxygenases and oxidoreductases are located at critical branch points in the biosynthesis and metabolism of cholesterol and vitamin D. These flavoproteins function as obligatory intermediates that accept 2 electrons from NAD(P)H with subsequent 1-electron transfers to a variety of cytochrome P450 (CYP) heme proteins within the mitochondria matrix (type I) and the (microsomal) endoplasmic reticulum (type II). The mode of electron transfer in these systems differs slightly in the number and form of the flavin prosthetic moiety. In the type I mitochondrial system, FAD-adrenodoxin reductase interfaces with adrenodoxin before electron transfer to CYP heme proteins. In the microsomal type II system, a diflavin (FAD/FMN)-dependent cytochrome P450 oxidoreductase [NAD(P)H-cytochrome P450 reductase (CPR)] donates electrons to a multitude of heme oxygenases. Both flavoenzyme complexes exhibit a commonality of function with all CYP enzymes and are crucial for maintaining a balance of cholesterol and vitamin D metabolites. Deficits in riboflavin availability, imbalances in the intracellular ratio of FAD to FMN, and mutations that affect flavin binding domains and/or interactions with client proteins result in marked structural alterations within the skeletal and central nervous systems similar to those of disorders (inborn errors) in the biosynthetic pathways that lead to cholesterol, steroid hormones, and vitamin D and their metabolites.
Studies of riboflavin deficiency during embryonic development demonstrate congenital malformations similar to those associated with genetic alterations of the flavoenzymes in these pathways. Overall, a deeper understanding of the role of riboflavin in these pathways may prove essential to targeted therapeutic designs aimed at cholesterol and vitamin D metabolism.
17. Content question: What do vitamin D and Riboflavin have in common?
16. Content question: What do vitamin D and vitamin C have in common?
by consuming a variety of grains what do we contribute to our diet? Calcium Potassium Riboflavin Vitamin D Vitamin C
l AT&T LTE 10:20 PM 55:26 Exit hich O vitamins? Thiamin, riboflavin, vitamin C Niacin, vitamin D, vitamin C A,C,D,K A,D,E,K 14 What would you recommend to someone who wants to make sure they get near the RDA for all vitamins? Eat a low of fresh fruits and vegetables Eat a lot of chicken and meat Eat a variety from all food groups daily Eat legumes three times per week
It's a yes or no question
Riboflavin (otherwise known as vitamin B,) is used to make Flaven MonoNucleotide (FMN), a critical redox prosthetic group within Complex I. A child suffering from food insecurities (hunger) has an undiagnosed vitamin Bdeficiency (too little vitamin Bin their diet). This child will also have very low FMN production FMN Complex Complex 1 - Normal B, Levels Very Low B, Levels How will this change impact activities of cellular respiration? Except for FMN within Complex...
QUESTION 56 2 points Save An kiwis to equal the vitamin C content of 1 You would have to eat papaya. kiwis do not have vitamin C 10 QUESTION 57 0.5 points (Extra Credit) Save Ansv PLP is a coenzyme for more than 100 enzymes which includes the primary enzymes for protein metabolism and is excreted from the _as PLP- albumin complex stomach liver intestine gall bladder QUESTION 58 0.5 points (Extra Credit) Save Answer and The vitamin is found...
Vitamin D is converted to its active form by the fat tissue and liver. kidneys and liver. skin and small intestine. skin and liver. small intestines and kidneys. Question 13 0 / 1 pts Which list contains only vitamins that do NOT function as coenzymes in energy metabolism? vitamin B6 and vitamin C choline and vitamin C biotin, pantothenic acid, riboflavin niacin, vitamin B6, folate thiamin, riboflavin, niacin UnansweredQuestion 14...
QUESTION 1 What vitamin improves iron absorption? Vitamin C Vitamin D Vitamin E Vitamin B-12 QUESTION 2 Which of the following is a good source of zinc? table salt, seaweed, dairy Bananas, oranges, potatoes Oysters, sirloin steak, peanuts Brazil nuts, fish, meat & organ meats QUESTION 3 Chromium deficiency results in .... high blood lipids high blood pressure impaired glucose uptake impaired cholesterol clearance QUESTION 9 During his wrestling workout, Damon loses about 4 pounds. He should consume cups of...
1. What do the following Vitamins do when looking at healing? Vitamin A: Vitamin B complex Vitamin C Vitamin D 2.What cells divide consonantly in the Human Body. 3. What organs have the ability to regenerate. 4. What are the acronyms RICE stands for? And when we apply this therapy 5. Black open pore Polyurethane Pour sponge inserted in the wound for what type of device positive or negative pressure device, what is this device called. 6. Jackson -Pratt drainage...
Incorrect Question 35 What do vitamins K and D have in common? Both are required for normal vision O Both are important in blood clotting. Both are important for bone health. O Neither has a set UL since there is no toxicity at high levels. Partial Question 37 1/2 pts (Select All That Apply) Triglycerides/fatty acids are classified by location of their double bonds hydrocarbon chain length saturation level the number of their double bonds Groups of people who are...
What vitamin acts as a coenzyme in cell respiration and is important in alcohol fermentation? O A. thiamine O B. riboflavin O C. niacin O D. pantothenic acid