Products for these reactions D3C Li D3C7OH D C HEBr Nal w NaSH, NaSH Br HONors...
1. Determine whether the following reactions go through SN or SNP and write the products, with stereochemistry as applicable. BrNHz NaOEt Nal OMS KCN CI DMSO Br HO NaSH DMSO Tso CH3 Nal Acetone CH3 2. The following reactions each undergo SNmechanisms. For each explain why you would predict the substitution products to come from an SN2mechanism and fill in the product. If stereochemistry is given in the reactants, give the correct stereochemistry in the products. Cl + Z Na...
1. Show the products of the following Sn2 reactions, including stereochemistry. Note: In all three cases, the solvent does not directly participate in the reaction (again, the solvents differ just so that the respective reactants all dissolve) and, as always, Nat is simply a spectator ion. a) EtOH Branche + NaOE EICH Hz + NaOEt acetone + Nal Phi Ph DMSO C YCHz + NaSH
1. Draw the transition state for the following SN2 reactions Br SH NaSH a. NaOH b. Br OH OH NaOH C. d. 2. Draw the concerted mechanism of the SN2 reactions from the previous question. a. b. C. d.
Which of the below Sn2 reactions will proceed most quickly? O H₂O CH3 -Br Nal Acetone CH3 H₃C Nal Br Acetone H₂C Br Nal Acetone CH3 Question 2 which the loans are insie Which of the below Sn1 reactions will proceed most quickly? me most author 0 H₃C- CH3 О нас OM 10 HO OH3Cm I Br CH, _"? H20 CH3
1. Provide the products of the following reactions. Write N.R. if there is no reaction happens. NH2 Nal Acetone CH COONa - foto 57 NaOM NaSH DBU EtOH NaCN EtONa Me- Br -Me
Draw the products of the reactions 1-6 CH3COOK attfort Br NASH CH3 DMF 7 H2O THE CH3 CH3 4) • BV Na3 > DMF CH2 CH3 (CH3)3 COK 5. ) CL 6. ) H₂ CC=C: Na THE
Provide the major products for the following reactions: Br Br d) e) Br Cl h) Br + i) Br
Question 5 Predict the major and minor products for the following reactions: а) NaSH Hас b) Br NaOEt Question 6 Predict the major and minor products for the following reactions: a) NaOEt CHa OTs With Tosylate (OTs)
4. In each case below identify: (a) the leaving group (b) the nucleophile, (c) and if the reaction is an Syl reaction or Sn2 reaction. (d) Draw the products of the following substitution reactions. NaSH DMSO MeOH H- Br NaCN DMF
4. In each case below identify: (a) the leaving group (b) the nucleophile, (c) and if the reaction is an Snl reaction or Sn2 reaction. (d) Draw the products of the following substitution reactions. NaSH DMSO MeOH H- Br NaCN DMF