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Question A1. Chlorpromazine was the first drug developed with specific antipsychotic action. The partial scheme below shows m(b) On the scheme, draw a possible structure for metabolite 1 in the appropriate box. (1 mark) (c) Metabolite 3 reacts furthe

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Answer #1

Phasel N-Oxidation HO Aromalio nxoners Phase 1 Phase-) flavin containing monooxyge lased Loxida UP Phase 1 Phase-21. N-Dealky

For prevention of formation of metabolite 2, Cholorpromazine should be reacted with FIASMA, as this is a functional inhibitor of acid sphingomyelinase.

Rest all answers are covered in the image @structures,phases,enzymes.

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