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Drug card for 2. Miotics, Direct Acting & Cholinesterase Inhibitor pilocarpine (Isopto Carpine)

Drug card for

2. Miotics, Direct Acting & Cholinesterase Inhibitor

  • pilocarpine (Isopto Carpine)

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Answer: Miotics drug which causes constriction of the pupil of the eye. The direct acting drugs pilocarpine is used in the strength of 0.25% to 10%. The mechanisim of action involved i.e. Pilocarpine reduces the intraocular pressure by increasing the aqueous flow which increases contraction of the longitudinal fibres of ciliary muscle. Pilocarpine is frequently combined with physostigmine in resistant cases of glaucoma. The cholinesterase inhibitors work by inactivating enzyme and as a result acetylcholine is freely permitted to exert its effects.

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