Compare and contrast the pharmacodynamics and pharmacokinetics between 2 of the 3 following populations: women, pediatrics,...
Compare and contrast the pharmacodynamics and pharmacokinetics between 2 of the 3 following populations: women, pediatrics, and geriatrics.
Homework Answers
Pharmacokinetics deals with liberation, absorption, distribution, metabolism and excretion pf drugs whereas pharmacodynamics deals with the relationship of drug dosage with different organs.
Age related Physiological differences between pardiatrics and women lead to differences in pharmacodynamics and pharmacokinetics between the two.
Factors influencing different mechanism of pharmacokinetics and pharmocodynamics between paediatrics and women include gastric pH and emptying time, intestinal transit time, immaturity of secretion and activity of bile and pancreatic fluid.
Other factors include membrane permeability, plasma protein binding and total body water.
The bioavailability and excretion snd metabolism of drug also differ in children and women.
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