You are a quality control chemist for a pharmaceutical company. You have been asked by your...
You are a quality control chemist for a pharmaceutical company. You have been asked by your laboratory manager to purchase a new chromatographic system to screen for potential impurities coming from the manufacturing process.
Which chromatographic system would you recommend for the separation of polar, low molecular weight, non-volatile impurities?
Homework Answers
I will recommend hydrophilic interaction chromatography with high performance liquid chromatography. Using this technology we can separate polar low molecular weight and non volatile impurities. These technology is widely use for separation of impurities from our compound
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