Drug A
Half life - 2.4hours
Volume of distribution - 18 L
Plasma concentration - 12mg/L
Formula :
Volume of distribution = clearance / KE( 0.015)
18L = clearance / 0.015
Clearance = 18×0.015
= 0.27
Infusion rate = clearance × concentration at steady state
= 0.27 × 12 mg
= 3.24 mg
Drug-A has an half-life of 2.4 hours and a volume of distribution of 18L. Calculate the...
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