Drug A has an half-life of 12 hours and a volume of distribution of 80 L....

Question

Question

Answer 1

Answer #1

The given values are :

Volume of distribution (Vd) = 80 litres

Plasma concentration (C0) = 0.4 micrograms/ ml , which is 400 micrograms / litre that is equal to 0.4mg/litre

Half life (t1/2) = 12 hrs

To calculate the total amount of drug in the body (D) ,

D = Vd × C0

D= 80×0.4 = 32 mg

So the amount of drug in the body when the plasma concentration is 0.4micrograms / ml is 32 mg.

Answer 2

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