Homework Answers
BJ is a 70 year old female who is administered a drug via continuous IV infusion....
BJ is a 70 year old female who is administered a drug via continuous IV infusion. The volume of distribution is 51 L and a half life of 19.8 hours. The drug concentration 19 hours after the infusion was started is reported to be 0.69 mg/L. What is the rate of infusion? Note: Assume the infusion is ongoing. Please provide your answer in units of mg/hr.
WK is a 60 year old female who is administered a drug via continuous IV infusion....
WK is a 60 year old female who is administered a drug via continuous IV infusion. The volume of distribution is 63 L and a half life of 16.8 hours. The drug concentration 29 hours after the infusion was started is reported to be 1.11 mg/L. What is the rate of infusion? Note: Assume the infusion is ongoing. Please provide your answer in units of mg/hr
EW is a 68 year old male who is administered a drug via continuous IV infusion....
EW is a 68 year old male who is administered a drug via continuous IV infusion. The volume of distribution is 56 L and a half life of 16.7 hours. The drug concentration 36 hours after the infusion was started is reported to be 1.84 mg/L. What is the rate of infusion? Note: Assume the infusion is ongoing. Please provide your answer in units of mg/hr:
A 199 lb patient is ordered to receive intermittent IV infusions of a drug. This drug...
A 199 lb patient is ordered to receive intermittent IV infusions of a drug. This drug has a population-based Vd of o. Lkg and a 6 hr elimination half-life. The ordering physician has indicated the rate of drug infusion should be 150 mg/hr for a total time of 2 hours. Assume the nurse will set the infusion pump to be 2 mL/min. You must now prepare the small volume parenteral bag containing the drug. What should be the drug concentration...
7. Smokers are known to have about 50% higher CL than nonsmokers for theophylline. If the...
7. Smokers are known to have about 50% higher CL than nonsmokers for theophylline. If the average observed AUC after administration of 300 mg IV theophylline in nonsmokers is 100 mg.hr/L, what is the expected AUC in smokers after administration of the same 300 mg dose? Theophylline undergoes linear pharmacokinetics 2. After administration of a single 400 mg dose of a drug, a linear plot of the serum concentration-time prorile on a semi-log graph paper showed a y-intercept of 1mg/mL...
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by...
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by multiple IV injections at 6-h intervals. The drug is water-soluble and has a distribution volume equivalent to that of total body water (50 liters). The drug has a biological half-life of 6 h. Calculate (Css (max), Css (min) and Cav(ss). The time necessary to reach 95% of the steady-state concentration. The number of doses required to reach 95% of the steady-state concentration.
kinteic Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient...
kinteic
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by multiple IV injections at 6-h intervals. The drug is water-soluble and has a distribution volume equivalent to that of total body water (50 liters). The drug has a biological half-life of 6 h. Calculate (Css (max), Css (min) and Cav(ss). The time necessary to reach 95% of the steady-state concentration. The number of doses required to reach 95% of the steady-state concentration.
A drug has linear pharmacokinetics, an half-life of 6 hours and a volume of distribution of...
A drug has linear pharmacokinetics, an half-life of 6 hours and a volume of distribution of 43L. How long it will take to reach 90% of steady state in a 33 year old patient receiving a 20mg/hr V-infusion? a. 20 hours b. 36 hours Oc. 142 hours Odinot enough information provided
A drug has a volume of distribution of 33L and a clearance of 4.3 L/hr. A...
A drug has a volume of distribution of 33L and a clearance of 4.3 L/hr. A steady state concentration of 5 mg/L is reached with the administration of 21.5 mg/hr IV-infusion. What is the amount in the body at steady state?
A drug (CL = 6 L/h, Va= 150 L) is to be administered as an IV...
A drug (CL = 6 L/h, Va= 150 L) is to be administered as an IV infusion. A steady-state plasma concentration of 1.2 mg L is desired. Calculate the following: (a) a suitable infusion rate, Rint (b) assuming it would take 4 half-lives to achieve the steady-state, how long would it take this drug to achieve this steady-state, tss (c) the value of a loading dose that would immediately achieve the desired steady-state plasma concentration of 1.2 mg/L, DL (d)...
WK is a 60 year old female who is administered a drug via continuous IV infusion. The volume of distribution is 63 L and a half life of 16.8 hours. The drug concentration 29 hours after the infusion was started is reported to be 1.11 mg/L. What is the rate of infusion? Note: Assume the infusion is ongoing. Please provide your answer in units of mg/hr
EW is a 68 year old male who is administered a drug via continuous IV infusion. The volume of distribution is 56 L and a half life of 16.7 hours. The drug concentration 36 hours after the infusion was started is reported to be 1.84 mg/L. What is the rate of infusion? Note: Assume the infusion is ongoing. Please provide your answer in units of mg/hr:
A 199 lb patient is ordered to receive intermittent IV infusions of a drug. This drug has a population-based Vd of o. Lkg and a 6 hr elimination half-life. The ordering physician has indicated the rate of drug infusion should be 150 mg/hr for a total time of 2 hours. Assume the nurse will set the infusion pump to be 2 mL/min. You must now prepare the small volume parenteral bag containing the drug. What should be the drug concentration...
7. Smokers are known to have about 50% higher CL than nonsmokers for theophylline. If the average observed AUC after administration of 300 mg IV theophylline in nonsmokers is 100 mg.hr/L, what is the expected AUC in smokers after administration of the same 300 mg dose? Theophylline undergoes linear pharmacokinetics 2. After administration of a single 400 mg dose of a drug, a linear plot of the serum concentration-time prorile on a semi-log graph paper showed a y-intercept of 1mg/mL...
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by multiple IV injections at 6-h intervals. The drug is water-soluble and has a distribution volume equivalent to that of total body water (50 liters). The drug has a biological half-life of 6 h. Calculate (Css (max), Css (min) and Cav(ss). The time necessary to reach 95% of the steady-state concentration. The number of doses required to reach 95% of the steady-state concentration.
kinteic
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by multiple IV injections at 6-h intervals. The drug is water-soluble and has a distribution volume equivalent to that of total body water (50 liters). The drug has a biological half-life of 6 h. Calculate (Css (max), Css (min) and Cav(ss). The time necessary to reach 95% of the steady-state concentration. The number of doses required to reach 95% of the steady-state concentration.
A drug has linear pharmacokinetics, an half-life of 6 hours and a volume of distribution of 43L. How long it will take to reach 90% of steady state in a 33 year old patient receiving a 20mg/hr V-infusion? a. 20 hours b. 36 hours Oc. 142 hours Odinot enough information provided
A drug has a volume of distribution of 33L and a clearance of 4.3 L/hr. A steady state concentration of 5 mg/L is reached with the administration of 21.5 mg/hr IV-infusion. What is the amount in the body at steady state?
A drug (CL = 6 L/h, Va= 150 L) is to be administered as an IV infusion. A steady-state plasma concentration of 1.2 mg L is desired. Calculate the following: (a) a suitable infusion rate, Rint (b) assuming it would take 4 half-lives to achieve the steady-state, how long would it take this drug to achieve this steady-state, tss (c) the value of a loading dose that would immediately achieve the desired steady-state plasma concentration of 1.2 mg/L, DL (d)...
Most questions answered within 3 hours.
-
> Women’s pulse rates are normally distributed with a mean of
68.5 beats per minute and...
asked 1 minute ago -
Briefly describe an aspect of the strengths perspective that is
consistent with your own understanding of...
asked 2 minutes ago -
Step by step method of using Sparse Identification of Nonlinear
Dynamics (SINDy) to model your own...
asked 10 minutes ago -
3) What are the typical social structures in a global city?
asked 3 hours ago -
Luther Corporation
Consolidated Balance Sheet
December 31, 2019 and 2018 (in $ millions)
Assets
2019
2018...
asked 3 hours ago -
(Expected rate of return and risk) Carter Inc. is evaluating a
security. Calculate the investment’s expected...
asked 6 hours ago -
What specific indicators can point to lack of progress for
African Americans in American society?
asked 7 hours ago -
1-The Electrons in a beam are moving at 2.7×108 m/s in an
electric field of 15000...
asked 7 hours ago -
A gas tank is a vertical cylinder. It has a radius of 1m, a
height of...
asked 7 hours ago -
Accent Software faces the following conditions. All of these
support Accent’s use of a market-penetration pricing...
asked 8 hours ago -
A mathematically inclined friend emails you the following
instructions: "Meet me in the cafeteria the first...
asked 8 hours ago -
A monopoly sells in two countries . The demand curves in the two
countries are p1...
asked 9 hours ago