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A drug has a volume of distribution of 33L and a clearance of 4.3 L/hr. A steady state concentration of 5 mg/L is reached wit
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Answer #1

Volume of distribution - 33L

Clearance = 4.3 L/hr

Concentration at steady state = 5mg/ L

Infusion dose = 21.5 mg/ hr

Amount of drug = concentration at steady state in plasma × volume of distribution at steady state

= 5mg/L × 33L

= 165 mg

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