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Response Questions Part A To B Hyperhidrosis is a stressful medical condition characterized by chronic excessive sweating. Primary hyperhidrosis is inherited and typically starts during adolescence. Botox was approved for treatment of hyperhidrosis in adults in 2004. A clinical trial examined the effectiveness of Botox for excessive armpit sweating in teenagers ages 12 to 17. Participants received either a Botox injection or a placebo injection (a simple saline solution) and were examined four weeks later to see if their sweating had been reduced by 50% or more. The two-way table shows the studys findings At least 50% reduction Total 104 108 Treatment Yes No 20 64 84 Botox 84 Total 128 212 (A) Find the marginal distribution of outcome (sweating reduced or not). (Enter your answer rounded to one decimal place.) At least 50% reduction: Not 50% reduction: What does this distribution tell us? Overall, the majority of subjects experienced a reduction in sweating of at least 50% Overall, the majority of subjects experienced a reduction in sweating equal to exactly 50% Overall, the majority of subjects experienced a reduction in sweating of at most 50% Overall, the majority of subjects experienced a reduction in sweating less than 50% (B) How do the outcomes for the teenagers in the study differ depending on which treatment they received? Use conditional distributions as a basis for vour answer In this study, a lesser proportion of patients given the Botox treatment experienced sweating relief than patients given a placebo. For example, 40.7% of the subjects given Botox experienced a reduction in sweating of at least 50% In this study, a greater proportion of patients given the Botox treatment experienced sweating relief than patients given a placebo. For example, 19.2% of the subjects given Botox experienced a reduction in sweating of at most 50% In this study, a much greater proportion of patients given the Botox treatment experienced sweating relief than patients given a placebo. For example, 80.8% of the subjects given Botox experienced a reduction in sweating of at least 50% In this study, a much lesser proportion of patients given the Botox treatment experienced sweating relief than patients given a placebo. For example, 59.3% of the subjects given Botox experienced a reduction in sweating of at most 50% What can you conclude about the effectiveness of Botox in treating excessive armpit sweating? There is not enough information to conclude whether Botox is ineffective Botox appears to be effective There is not enough information to conclude whether Botox is effective Botox appears to be ineffective

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Answer #1

a) at least 50% reduction
128/212
= 60.4%

not 50% reduction
= 39.6%

option A) is correct

b)
84/104=80.8%
option C) is correct

conclusion

option B) is correct

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