Question

Ibuprofen and coronavirus: Should you take ibuprofen now?

Please provide a view point on this topic and include the following in the response:

a.) what is composition of ibuprofen

b.) toxicity or side effects of ibuprofen

c.) why is ibuprofen used

d.) what is coronavirus

e.) why should ibuprofen be used or not

f.) what ibuprofen does to coronavirus infected patients.

Answer 1

1) ibuprofen can be used in coronavirus infection as a anti inflammatory drug,There is currently no strong evidence that ibuprofen can make coronavirus (COVID-19) worse, and the use of paracetamol for COVID-19 is promoted.

a) active ingredient is  Ibuprofen, which is (±) -2 - ( p - isobutylphenyl) propionic acid., it is a Non steroidal anti inflammatory drug(NSAID).

B)SIDE EFFECT OF IBUPROFEN

• Stomach pain and heartburn.
• Stomach ulcers.
• Nausea, vomiting, diarrhea or constipation.
• Allergic reactions.
• Liver or kidney problems.
• High blood pressure.

C) ibuprofen is used for

• Reduce pain.
• Decrease fever.
• Decrease inflammation.

d)

Coronaviruses cause acute, mild upper respiratory infection (common cold).

Structure

Spherical or pleomorphic enveloped particles containing single-stranded (positive-sense) RNA associated with a nucleoprotein within a capsid comprised of matrix protein. The envelope bears club-shaped glycoprotein projections.

Classification

Coronaviruses (and toroviruses) are classified together on the basis of the crown or halo-like appearance of the envelope glycoproteins, and on characteristic features of chemistry and replication. Most human coronaviruses fall into one of two serotypes: OC43-like and 229E-like.

Multiplication

The virus enters the host cell, and the uncoated genome is transcribed and translated. The mRNAs form a unique “nested set” sharing a common 3′ end. New virions form by budding from host cell membranes.

Pathogenesis

Transmission is usually via airborne droplets to the nasal mucosa. Virus replicates locally in cells of the ciliated epithelium, causing cell damage and inflammation.

Host Defenses

The appearance of antibody in serum and nasal secretions is followed by resolution of the infection. Immunity wanes within a year or two.

Diagnosis

Colds caused by coronaviruses cannot be distinguished clinically from other colds in any one individual. Laboratory diagnosis may be made on the basis of antibody titers in paired sera. The virus is difficult to isolate. Nucleic acid hybridization tests (including PCR) are now being introduced.

Control

Treatment of common colds is symptomatic; no vaccines or specific drugs are available. Hygiene measures reduce the rate of transmission.

f)ibuprofen are helpful for symptomatic treatment only and are not a cure. By decreasing inflammation, they can decrease pain, swelling, redness” and other symptoms that may be associated with inflammation.