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A follow-up study was conducted over a five year period to determine the incidence of DVT...

A follow-up study was conducted over a five year period to determine the incidence of DVT in women with the Factor V Leiden (n= 1000) who were taking oral contraceptives compared to women without the Leiden factor who were also taking OCs (n=1050). During the study period, DVTs occurred in 450 women with a +Factor V Leiden and in 15 women without the Leiden Factor. a. What type of study was this? _____________________________________ b. Please calculate the RR by completing a 2x2 table and using the formula for RR

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Answer #1

Ans A. Cohort, or "longitudinal", or "prospective" studies.

Ans B.

DVT (Yes) DVT (No) Total
Factor V Leiden (Yes) 450 550 1000
Factor V Leiden (No) 15 1035 1050
Total 465 1585 2050

RR= 450/1000 / 15/1050 = 45

  • Therefore, the relative risk of acquiring DVT with +Factor V Leiden is 45
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