Question

Which of the following describes the cause of the pathologic reduction in vascular resistance in sepsis?

A. Nitric oxide mediated arterio- and venodilation

B. Marked increase in venous capacitance

C. Fluid Loss

D. All of the above

E. None of the above

Based on the Surviving Sepsis Campaign guidelines and the Tenet standard, the 6 hour bundle for severe sepsis with persistent hypoperfusion consists of all of the following except?

A. Remeasure lactate if initial lactate was elevated > 2.0mmol/L

B. Administer vasopressors to maintain a mean arterial pressure (MAP) ≥ 65 mm Hg

C. Obtain CVP measurement

D. A and B only

E. All of the above

Tenet guidelines, based on the Surviving Sepsis Campaign and Tenet standard, the required fluid bolus for a patient identified as having severe sepsis is which of the following?

A. Minimum of 50 mL/kg Normal Saline or Lactated Ringers

B. Minimum of 30 mL/kg Normal Saline or D5W

C. Minimum of 1000 mL over 30 minutes

D. Minimum of 30 mL/kg Normal Saline or Lactated RingersE. Minimum of 500cc Normal Saline or Lactated Ringers

Which of the following is true about severe sepsis?

A. It is the 10th leading cause of death in the US

B. Kills more people than heart disease each year

C. Is more severe than septic shock

D. Over 4 million cases of severe sepsis worldwide each year

E. Primarily affects women and children

Answer 1

ANSWER.

A. Nitric acid mediated arterio and venous dilation is the cause of pathologic

      reduction in vascular resistance.

E. 6hr bundle for severe sepsis with persistent hypoperfusion consists of

           A. Remeasure the lactate if the intial lactate was elevated >2 mmol/L.

          B. Administer vasopressor to maintain mean arterial pressure(MAP) > 65 mm HG.

           C.Obtain CVP measurement.

D. Minimum of 30 mL/kg Normal saline or Lactate ringers.

     required fluid bolus for a patient with severe sepsis.

A. Severe sepsis is the 10th leading cause of death in U.S.