What is the COX-2 hypothesis? What pharmaceutical agent was produced as a result of this hypothesis?...
What is the COX-2 hypothesis? What pharmaceutical agent was produced as a result of this hypothesis? What adverse effects were prominent in patients that took this drug?
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What is the COX-2 hypothesis? What pharmaceutical agent was
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11. A biotechnology company called Intercept Pharmaceutical, focused on development of drug for l...
11. A biotechnology company called Intercept Pharmaceutical, focused on development of drug for liver fibrosis disease called NASH announced that its experimental drug called OCA was experimented on 930 patients (465 in placebo group and 465 in 25 mg OCA group ) and the patients were followed up for 18 months. The result is as follows: 23.1% patients taking 25 mg of OCA versus 11.1% of placebo patients showed fibrosis improvement Serious adverse effects of 28% (OCA group) versus 19%...
1 , A pharmaceutical lab did an extensive analysis on a drug and found that the...
1 , A pharmaceutical lab did an extensive analysis on a drug and found that the drug causes negative side effects in 3 of every 100 patients. To confirm this affirmation, another laboratory chooses 5 people at random who have consumed the drug. What is the probability of the following events? a. None of the five patients experience side effects. (5 points) b. At least two experience side effects. (5 points) c. What is the average number of patients that...
1. A pharmaceutical company is testing a new cold medicine to determine if the drug has...
1. A pharmaceutical company is testing a new cold medicine to determine if the drug has side effects. To test the drug, 7 patients are given the drug and 8 patients are given a placebo (sugar pill). The change in pulse rate (beats per minute) after taking the pill was as follows: Given drug: 3 5 2 8 2 5 5 Given placebo: 2 4 1 1 3 0 2 4 Test to determine if the drug raises patients’ pulse...
A large study showed that aspirin reduced the rate of first heart attacks. A pharmaceutical compa...
A large study showed that aspirin reduced the rate of first heart attacks. A pharmaceutical company thinks that they have a drug that will be more effective than aspirin, and plans to do a randomized clinical trial to test the new drug. They determine the following null and alternative hypotheses: Example 2: a) Ho: the new drug is not more effective than aspirin HA: the new drug is more effective than aspirin hey conduct the trial. The group that used...
Question: A pharmaceutical company has developed a new cancer treatment for pancreatic cancer, one of the...
Question: A pharmaceutical company has developed a new cancer treatment for pancreatic cancer, one of the most deadly diagnoses. The current 5 year survival rate for stage I pancreatic cancer is 15% with a population standard deviation of 2%, and the average 5 year survival of a SRS of 82 patients enrolled in a study sponsored by the company was 19%. A) Using α=.01, answer the question as to whether or not the new treatment is successful at increasing 5...
f Adverse reactions of a drig used to help pašents contrue tho abstinence from the use of alcohol have been studied in drical trial, and die accompanying table summarizes at adverse re...
f Adverse reactions of a drig used to help pašents contrue tho abstinence from the use of alcohol have been studied in drical trial, and die accompanying table summarizes at adverse reaction in the digestive syste i EE Cick the keon to view the data on advarse seactions from treatments Detormine he nul and abernative hypotheses O A. Ho: Tho drug treatment does not resul is independent of the treatment group Does the drug treatment appear to have an reslts...
If you were a member of the drug development committee at a pharmaceutical sponsor, how would...
If you were a member of the drug development committee at a pharmaceutical sponsor, how would you draft a package insert indication for a new lipid lowering drug that is proven more potent than atorvastatin. The new drug is called lowerstatin. Please check my assignment below and make corrections or add something if needed also I did not know what to write for Adverse reactions Drug Name: Lowerstatin Drug classification: Lipid-lowering agent. Clinical pharmacology A dose of 20 mg per...
Story: The musculoskeletal system provides form, stability, and movement to the human body. Musculoskeletal disorders cause...
Story: The musculoskeletal system provides form, stability, and movement to the human body. Musculoskeletal disorders cause impaired movement, pain, and damage to muscles, bones, and/or joints. Injuries to the skeletal system are common in people of all ages and range in severity. A variety of classifications of medications are used in treatment which include anti-gout, bisphosphonates, calcium, COX-2 inhibitors, corticosteroids, DMARS, and muscle relaxants. Medications to treat pain include NSAIDS, salicylates, acetaminophen, and opioids. The reason we’re having this discussion forum...
A pharmaceutical company wants to answer the question of whether it takes longer than 45 seconds...
A pharmaceutical company wants to answer the question of whether it takes longer than 45 seconds for a drug in pill form to dissolve in the gastric juices of the stomach. A sample was taken from patients taken the given drug in pill form and times for the pills to be dissolved were measured as the following 42.7 , 43.7 , 44.6 , 45.1 , 45.6 , 45.9, 46.8 , 47.6 A. State the hypotheses to test this question B....
A pharmaceutical company believes its Alzheimer’s drug may have an effect on cortical atrophy. If it...
A pharmaceutical company believes its Alzheimer’s drug may have an effect on cortical atrophy. If it decreases cortical atrophy, it may be a promising candidate for further drug trials; if it increases cortical atrophy, it may provide insight into the mechanism of Alzheimer’s disease. Thus the company decides to test the drug on rats, as either result may hold future benefits. Among 115 transgenic rats (genetically engineered to induce Alzheimer’s), 65 rats receive the drug over 6 months, 50 rats...
11. A biotechnology company called Intercept Pharmaceutical, focused on development of drug for liver fibrosis disease called NASH announced that its experimental drug called OCA was experimented on 930 patients (465 in placebo group and 465 in 25 mg OCA group ) and the patients were followed up for 18 months. The result is as follows: 23.1% patients taking 25 mg of OCA versus 11.1% of placebo patients showed fibrosis improvement Serious adverse effects of 28% (OCA group) versus 19%...
1 , A pharmaceutical lab did an extensive analysis on a drug and found that the drug causes negative side effects in 3 of every 100 patients. To confirm this affirmation, another laboratory chooses 5 people at random who have consumed the drug. What is the probability of the following events? a. None of the five patients experience side effects. (5 points) b. At least two experience side effects. (5 points) c. What is the average number of patients that...
A large study showed that aspirin reduced the rate of first heart attacks. A pharmaceutical company thinks that they have a drug that will be more effective than aspirin, and plans to do a randomized clinical trial to test the new drug. They determine the following null and alternative hypotheses: Example 2: a) Ho: the new drug is not more effective than aspirin HA: the new drug is more effective than aspirin hey conduct the trial. The group that used...
f Adverse reactions of a drig used to help pašents contrue tho abstinence from the use of alcohol have been studied in drical trial, and die accompanying table summarizes at adverse reaction in the digestive syste i EE Cick the keon to view the data on advarse seactions from treatments Detormine he nul and abernative hypotheses O A. Ho: Tho drug treatment does not resul is independent of the treatment group Does the drug treatment appear to have an reslts...
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