Homework Answers
Lymphomas arise;
From abnormal proliferation of the T lymphocytes (As Lymphomas arise from mature T cells and they are a type of cancer so involve uncontrolled proliferation)
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Question 40 What causes lymphomas? O They develop in the precursor cells of the bone marrow....
GVHD develops when O A. the bone marrow does not produce any blood cells OB. a...
GVHD develops when O A. the bone marrow does not produce any blood cells OB. a patient's immune system rejects a donor organ O C. the clotting time is prolonged due to factor VIII deficiency OD. Epstein-Barr virus causes an infection
Question 4 1 pt Which of the following is true of B cells (select ALL that...
Question 4 1 pt Which of the following is true of B cells (select ALL that apply): born in the bone marrow O can differentiate into plasma cells some types can directly kill a target cell mature in the bone marrow born in the thymus mature in the thymus make antibodies can differentiate into memory cells are considered "antigen-presenting" cells Question 5 1 pts B cell activation requires (select ALL that apply): antiren binding to antibody on B cell surface
just question #2 Lymphocyte Development 1. B cell development in the bone marrow shares may features...
just question #2
Lymphocyte Development 1. B cell development in the bone marrow shares may features with T cell development in the thymus. A) Discuss what you consider to be the two major goals of lymphocyte development (i.e. what is the purpose of the Bone marrow and Thymus environments). B) Describe what occurs during the Precursor B cell stage and identify/describe the analogous stage in T cells. 2. With regards to what we've discussed regarding T cell development and alloreactivity,...
1. At the molecular level, what drives B cell development in the bone marrow? 2. What...
1. At the molecular level, what drives B cell development in the bone marrow? 2. What is the role of stromal cells in B cell development in the bone marrow? 3. Describe the sequence of events in B cell development with respect to rearrangement of heavy and light chain Ig genes. 4. Why does Ig gene rearrangement often fail to produce a functional protein product? What mechanisms exist to overcome this problem? 5. What is “allelic exclusion” and what is...
4. A) At high doses, AZT had serious side effects especially on bone marrow cells. Based...
4. A) At high doses, AZT had serious side effects especially on bone marrow cells. Based on the structure of AZT and how you think the inhibitor works, what do you think is the cause? B) The data below helps us to understand both how AZT affects the enzyme reverse transcriptase and how it may affect other cells. Interpret this data in light of your answers to part a. Why do you think bone marrow cells would be affected more...
Question 22 1 pts How do naïve and mature lymphocytes differ? Mature lymphocytes cannot bind to...
Question 22 1 pts How do naïve and mature lymphocytes differ? Mature lymphocytes cannot bind to antigens Naive lymphocytes can differentiate to become either B or T cells; Mature lymphocytes are cells that have made that decision and cannot switch back. O Mature lymphocytes have not encountered an antigen before Nalve lymphocytes have not encountered an antigen before Naive lymphocytes cannot bind to antigens
hone madtions are systemic and not isolated to a and leukemi ue Tinates in bone marrow,...
hone madtions are systemic and not isolated to a and leukemi ue Tinates in bone marrow, and leukema outo of lym eukocymetaading to their type and the specific lymph nodes involved when ecept Or ssified acil myeloma is classified as to whether it is stated to be in a that forms in the blood with proliferation of discussed previously does not apply to these neoplasms tes. These that ornginates in t ing and the concept of metastatditions de. the diagnosis...
Interpret this data. Why do you think bone marrow cells would be affected more than other...
Interpret this data. Why do you think bone marrow cells would be
affected more than other cell types?
4. The data below helps us to understand both how AZT affects the enzyme that you named above and how it may affect other cells. Interpret this data in light of your answers to the previous questions. Why do you think bone marrow cells would be affected more than other cell types. Fraction of Enzyme bound to Inhibitor Human DNA dependent RNA...
Indicate what step is correct (Select all that apply) Lymphocytes travel through the body in the...
Indicate what step is correct (Select all that apply) Lymphocytes travel through the body in the lymph as well as the blood Lymphocytes leave the blood through the walls of fine capillaries in 2ry lymphoid organs After spending some time in the LN, lymphocytes leave in the efferent lymph Lymphocytes return to blood at the subclavian vein A lymphocyte after encounter an antigen to which its receptor binds, stops recirculating. The spleen has no connection to the lymphatic system Lymphocytes...
45. Antigens can be found on... (a) flagella (b ell walls (c) human cells (@a 46....
45. Antigens can be found on... (a) flagella (b ell walls (c) human cells (@a 46. What is the site where stem cells develop and mature into T lymphocytes in humans (b) thymus (c) blood (d) bone marrow b) cell walls (c) human cells (d) all of the above develop and mature into T lymphocytes in humans? (a) spleen 41. Antigen presentation with MHC I molecules sensities which type of T cell? (a) cytotox C (b) helper T cells (c)...
GVHD develops when O A. the bone marrow does not produce any blood cells OB. a patient's immune system rejects a donor organ O C. the clotting time is prolonged due to factor VIII deficiency OD. Epstein-Barr virus causes an infection
Question 4 1 pt Which of the following is true of B cells (select ALL that apply): born in the bone marrow O can differentiate into plasma cells some types can directly kill a target cell mature in the bone marrow born in the thymus mature in the thymus make antibodies can differentiate into memory cells are considered "antigen-presenting" cells Question 5 1 pts B cell activation requires (select ALL that apply): antiren binding to antibody on B cell surface
just question #2
Lymphocyte Development 1. B cell development in the bone marrow shares may features with T cell development in the thymus. A) Discuss what you consider to be the two major goals of lymphocyte development (i.e. what is the purpose of the Bone marrow and Thymus environments). B) Describe what occurs during the Precursor B cell stage and identify/describe the analogous stage in T cells. 2. With regards to what we've discussed regarding T cell development and alloreactivity,...
4. A) At high doses, AZT had serious side effects especially on bone marrow cells. Based on the structure of AZT and how you think the inhibitor works, what do you think is the cause? B) The data below helps us to understand both how AZT affects the enzyme reverse transcriptase and how it may affect other cells. Interpret this data in light of your answers to part a. Why do you think bone marrow cells would be affected more...
Question 22 1 pts How do naïve and mature lymphocytes differ? Mature lymphocytes cannot bind to antigens Naive lymphocytes can differentiate to become either B or T cells; Mature lymphocytes are cells that have made that decision and cannot switch back. O Mature lymphocytes have not encountered an antigen before Nalve lymphocytes have not encountered an antigen before Naive lymphocytes cannot bind to antigens
hone madtions are systemic and not isolated to a and leukemi ue Tinates in bone marrow, and leukema outo of lym eukocymetaading to their type and the specific lymph nodes involved when ecept Or ssified acil myeloma is classified as to whether it is stated to be in a that forms in the blood with proliferation of discussed previously does not apply to these neoplasms tes. These that ornginates in t ing and the concept of metastatditions de. the diagnosis...
Interpret this data. Why do you think bone marrow cells would be
affected more than other cell types?
4. The data below helps us to understand both how AZT affects the enzyme that you named above and how it may affect other cells. Interpret this data in light of your answers to the previous questions. Why do you think bone marrow cells would be affected more than other cell types. Fraction of Enzyme bound to Inhibitor Human DNA dependent RNA...
45. Antigens can be found on... (a) flagella (b ell walls (c) human cells (@a 46. What is the site where stem cells develop and mature into T lymphocytes in humans (b) thymus (c) blood (d) bone marrow b) cell walls (c) human cells (d) all of the above develop and mature into T lymphocytes in humans? (a) spleen 41. Antigen presentation with MHC I molecules sensities which type of T cell? (a) cytotox C (b) helper T cells (c)...
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