What is the target AUC for a patient with a GFR 60 mL/min who is ordered...

Question

Question

What is the target AUC for a patient with a GFR 60 mL/min who is ordered carboplatin 425 mg?

Answer 1

Answer #1

ANSWER.

* Calculation of target AUC.

Formula

Target AUC = Carboplatin dose / (GFR + 25).

Here

Carboplatin dose = 425 mg.

GFR = 60 mL/min.

As per formula

Target AUC = 425 / (60+25)

= 425 / 85

= 5

d) Target AUC = 5

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Answer 2

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