Question

From the information in Chapter 8 on metabolism and Appendix A, we can see the multiple metabolic pathways involved in generating ATP from the breakdown of the nutrients glucose, protein and fats. Glycolysis generates pyruvate, the pyruvate then becomes Acetyl CoA, which enters the Krebs Cycle (TCA), products of the Krebs Cycle then enter the Electron Transport Chain (ETC) where ATP is the final product. Fat breakdown (beta-oxidation) also generates Acetyl CoA, which then enters the Krebs Cycle to produce ATP also. Oxygen must be present in order for the ETC to produce ATP. Without oxygen (anaerobic metabolism), glycolysis produces lactic acid.

1. The above pathways show that there must always be some carbohydrate present for the Krebs Cycle to progress. What advice would you provide to someone following a low carbohydrate diet (non-medical)?

2. What is a source the body could use to create glucose if carbohydrates are in low supply?

Answer 1

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