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Ordered: Plicamycin (Mithracin) 2.5 mg IV daily. Patient’s weight: 98 kg Therapeutic dosage range: 25 to...

Ordered: Plicamycin (Mithracin) 2.5 mg IV daily. Patient’s weight: 98 kg Therapeutic dosage range: 25 to 30 mcg/kg/day.

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Answer #1

Given

Order:Mithracin

Dose:2.5mg (2500mcg) ie.,2.5×1000

Route:IV

Frequency:daily

Weight:98kg

Therapeutic range =25 to 30mcg/kg/day

If 1kg =25mcg

then 98kg=??mcg

Cross multiply and divide

=98×25÷1

=2450mcg/day

Now for 30mcg

When 1kg=30mcg

Then 98kg=??mcg

=30×98÷1

=2940mcg/day

Ans:The therapeutic dosage range is 2450mcg to 2940mcg/day

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