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In cells that have been signaled to die via TNF-a receptor signaling but lack caspase-8 activity a. apoptosis occurs via the
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Answer #1

Answer: Option A

Explanation:

  • Activation of caspase 3,6,7 leads to Apoptosis.
  • This activation can be mediated by caspase 8.
  • When caspase 8 is inactive, other caspase such as 2, 1 can mediate the activation of caspase 3,6,7, which ultimately lead to Apoptosis.
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