Question

Which of the following is not directly responsible for producing a 2nd messenger when cells respond...

Which of the following is not directly responsible for producing a 2nd messenger when cells respond to extracellular signals?

A) Receptor Kinase

B) Phospholipase

C) Adenyl Cyclase

D) All of the above produce 2nd messengers

I believe they are all involved in the production of 2nd messengers, no?

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Answer #1

The one which is not directly responsible for producing a 2nd messenger when cells respond to extracellular signals are :

All of the above produce secondary messengers

a) Receptor kinase : Example receptor tyrosine kinase (RTK) that phosphorylates many proteins and involves in the production of secondary messengers like ras upon phosphorylation. Hence it is produced indirectly or via a other proteins.

b) Phospholipase : Example phospholipase C produce two secondary messengers like DAG (diacyl glycerol) and IP3 (1,4,5 -Inositol triphosphate. It is produced directly by activation

c) Adenyl cyclase : Adenyl cyclase (AC) produce secondary messenger like cAMP (Cyclic Adenosine monophosphate). It is produced directly by activation

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