1. NaBH4, CH3OH eo 2. HCI, H20 1. NaBH4 (1 eq.), CH3OH 2. HCI, H2O os Ο 1. NaBH(OCH3)3, (1 eq.), CH3OH 2. HCI, H2O & 1. LIAIH4 (1 eq.), THF 2. HCI, H20
For each reacuon ere s only as an aid for you. 1) KOH, H-O, heat Diethyl malonate B 1) Ph3P, ether 2) nBuLi, ether CIH1204 2) H, H2O, heat C1SH2406 CHH1202 NaOEt, EtOH Br OCH2CH3 3) PHCHO NH/heat Note: The C-13 NMRS for Structures C, D, and E each show 7 resonances LIAIH D E C1HNO ether C1H1SN Br 1) SOCI2, pyridine F 2) CH3OH 1) CH2COCI,AICI3 1) Mg(s), Et20 H 2) diisopropyl amine, pH 4.5, NaBH3CN 2) CO2 (s)...
Which set of conditions will achieve the transformation shown? 1. LIAIH4; 2. H /H20; 3. (CH3)2CHNH2 (exCess) 1. LIAIH4; 2. H*/H2O; 3. NaBr; 4. (CH3)2CHNH2 (excess) 1. CH3MgI; 2. H*/H2O; 3. (CH3)2CHNH2 (excess) 1. CH3M9I; 2. H*/H20; 3. TosCl; 4. (CH3)2CHNH2 (excess) 1. (CH3)2CHNH2; 2. LIAIH4; 3. H20
20) 20) Which of the following syntheses gives 3-methyl-1-hexanol? O Mg 1) A) 2-bromopentane diethyl ether 2) Mg B) 2-bromohexane - diethyl ether 1) HC=0 2) H C) 3-bromopentane Mg diethyl ether 1) CH2CH=0 2) H Mg D) 1-bromobutane diethyl ether 1) CH3CCH; 2) D)D А) А В) В c) C 21) Identify the reagent needed to carry out the following conversion. 21) 0 CHOH CHOH ?, CH CH B) PCC/CH2Cl2 D) K2Cr2O7, H2SO4/H20 A) Os04 C) HIO4
Predict the products. 1, SOCI N'CO NH2 CH3NCO + water (1) LiAIH4 (2) H20 (1) LiAIH4 (2) H20 (1) NaBH4 (2) H20 (1) LiAlH4 (1) Lalhas (2) H2O inion (1) LIAIH4 (2) H20 (1) NaBH4 (2) H20
1. HBr, H2O2 2. NaCN 3. HCI, H2O, heat 4. SOCI 5. NH3 6. LIAIH4 7. H20 Work out the synthesis on a separate sheet of paper, and then draw the structure of the final organic product. • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading. • Do not draw organic or inorganic by-products.
Select the major product of the following reaction. + Mg/diethyl ether 1. 2.H20* Y YY YYY 01 O IV O III Ono reaction
Predict the products. 16. K2Cr207 (excess) H2SO4, H2O HO 1. Phli, Et20 2. HCI, H20 3. SOCI2, Etz 4. NaOAC 1. Mg (1 eq), Et O Br 2. (1 eq) | C-CHO 3. HCI, H20 1. NaBH, MeOH, 0°C 2. PBrz. THE 3. LiAIDA, THE 4. HCI, H20 1. SOCI, NEtz, THE CHO 2. 2 eq Li, hexane 3. HCI, H20 hint: multiple steps 1. LiAlH4, THE 2. HCI, H2O 3. PBr3, THE 1. PCC, DCM OH 2. Mg, Eto...
Draw the major product for each reaction. он. CH3 heat N(CH3)3 a. LiAIH4, Et20 b. H30*/H20 1. NaCN, DMSO Br 2. a. LiAIH4. THF b. H3O+/H2O 1. NaN3, DMSO Br 2. a. LiAIH4, THF b. H3O /H20 1. HNO3, H2SO4 2. SnCl2 3. Br2 4. a. HNO2, H2SO4 H3C b. H2PO2 NH2 1. NaNO2, HCI, H20 но 2. HBF4
1. LiAIH4, Eto 2. HC/H20 1. LiAIH4, Et20 2. HCUH2O 1. LiAlH4, Et20 2. HCUH20 1. NaBH4, EtOH 2. HC/H2O 1. NaBH4, EtoH 2. HCVH2 Stud