Which of the following would be the consequence if the promoter of a gene has been...
Which of the following would be the consequence if the promoter of a gene has been mutated so that it is no longer recognized by a sigma factor?
A. Nothing, RNA polymerase is still able to bind.
B. Capping of transcripts would be affected in those specific genes.
C. Transcription of many genes regulated by the same sigma factor would be disrupted.
D. RNA polymerase would require priming in order to transcribe new messages.
E. Transcription of only that gene would be disrupted.
Homework Answers
c) transcription of many genes regulated by the same sigma factor would be disrupted.
- sigma factor function in prokaryotes and not in eukaryotes.
- sigma factor is involve in transcription by allowing the RNA polymerase to bind to the specific promoter.
- sigma factor increases the specificity of the RNA polymerase for the specific DNA sequence
- there are many sigma factor such as sigma 70 ( most common ) , sigma 32, 28, 54 and so on.
- when promoter get mutated the sigma factor cannot recognised the promoter , the transcription of that gene will not occur because RNA polymearse does not bind.
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