left side 1) Translation middle 1) PrPsc - induced misfolding Right side 1) Transcription
of PrPsc 2) Normal function
3) Abnormal function
Neuronal cell Prop Nucleus Prpse-induced misfolding of Prpo DNA Translation Transcription Prpc (normal prion) Normal function...
Fill in the diagram below to show the relationship between DNA and proteins. Nucleus Translation Transcription Ribosome
Assuming transcription and translation are taking place simultaneously, is the cell below a eukaryotic or prokaryotic cell? Please explain your answer. RNA polymerase DNA Ribosome Transcription Polypeptide- Translation MRNA
List the steps involved in the transcription and translation of DNA into mRNA and tRNA in order? DNA replicated to RNA tRNA translates mRNA and adds amino acids to the growing peptide chain making a protein mRNA leaves nucleus Introns are excised from hnRNA Addition of 5' cap and poly-A tail to mRNA
ALS is caused by the accumulation of misfolded protein that eventually leads to neuronal cell death. Just as is the case with prion diseases (e.g., Mad Cow disease), there is a spreading effect: even the presence of a small amount of misfolded (e.g., mutant) protein can cause other WT proteins of the same kind to become misfolded, which join the large misfolded aggregate forming in diseased cells. This is the principle mechanism thought to be behind the spreading of neurodegeneration...
In any creature, a transcription factor must: 1. get into the nucleus 2. bind to DNA 3. control the RNA polymerase 4. respond to external or internal signals. 5. be allosteric. 6. block the polymerase 7. localize (somehow) to DNA 8. be controlled by transcription and translation. O O 1, 2, 3. O1, 3, 5. 1, 4, 7. O O O O O 1,4,5. O 2,5, 8. O 3, 4,7 3, 6, 8. 4,5,6. 4, 6, 8. O O O
You want to track translation of your transcription factor within a pancreatic cell for your Excellence in Research project. You perform a pulse-chase experiment, where radioactive amino acids are introduced to the cell over a short period of time (pulse) and then are washed away (chase). The radioactive amino acids will be introduced into newly synthesized protein and you can track the radioactive proteins as they are sorted throughout the cell. You also add a drug that prevents translation of...
Which of the following proteins is NOT involved in DNA virus induced cell transformation? a) T antigen b) retinoblastoma protein (Rb) c) E2f transcription factors d) Pkr e) p53
Neuronal cell death during embryonic development of the mammalian brain: a. is a normal and desirable event. b. always results in loss of function. c. always results in decreased complexity of the remaining neural network. d. occurs in the small brain of the rat, but not in the large brain of the human.
11. Deoxyribose 12. 13. 14. 15. 16. Nucleus Point mutation Deletion mutation Exons Translation Nitrogenous bases H bonded mRNA A. Molecule that carries instructions for making a protein from a gene in the nucleus to a ribosome in the cytoplasm B. Enzyme that unwinds DNA double helix C. Sugar found in DNA nucleotide D. Process of making a protein E. Substitution of one nucleotide base pair for another F. Rungs (steps) of DNA "ladder" G. Transcription occurs in this part...
1. Transcription occurs in the a. Nucleus. b. Ribosomes of the Rough Endoplasmic Reticulum. c. Mitochondrion. d. Cell membrane. e. Smooth Endoplasmic Reticulum. 2. The monomers of DNA and RNA are a. amino acids. b. monosaccharides. c. nucleotides. d. fatty acids. e. nucleic acids. 3. Which of the following statements regarding DNA is false? a. DNA uses the nitrogenous base uracil. b. DNA is a nucleic acid. c. One DNA molecule can include four different nucleotides in its structure. d....