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Neuronal cell Prop Nucleus Prpse-induced misfolding of Prpo DNA Translation Transcription Prpc (normal prion) Normal function

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Neuronal cell Prop Nucleus Prpse-induced misfolding of Prpo DNA Translation Transcription Prpc (normal prion) Normal function

left side 1) Translation middle 1) PrPsc - induced misfolding   Right side 1) Transcription

of PrPsc 2) Normal function

3) Abnormal function

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