Question

Type your answer in the box. 1 dose to the The therapeutic index is the ratio of the dose that is used to assess the safety and reliability of the drug.

Answer 1

1. Therapeutic index is the ratio of the dose that produces toxicity (lethal effect)in 50% population dose to the dose producing a specified therapeutic effect.

2.

A. Used for chemotherapy. Antimicrobial drugs have different mode of action can inhibit cell wall, membrane, alter cell memrane, inhibit nucleic acid synthesis of pathogen.

B. Selective toxicity

C. Minimum inhibitory concentration