8) The Na+/K+-ATPase enzyme helps cells maintain their membrane potential. For every (1/2/3/4) sodium ions that are (Pumped in/Pumped out), (1/2/3/4) potassium ions are (Pumped in/Pumped out)
Answer:
The Na+/K+-ATPase enzyme helps cells maintain their membrane potential. For every 3 sodium ions that are Pumped out, 2 potassium ions are Pumped in.
Explanation:
Mechanism of sodium potassium pump
- The pump, after binding ATP, binds 3 intracellular Na+
ions.
- ATP is hydrolyzed, leading to phosphorylation of the pump at a
highly conserved aspartate residue and subsequent release of
ADP.
- A conformational change in the pump that exposes the Na+ ions to the outside. The phosphorylated form of the pump has a low affinity for Na+ ions, so they are released.
- The pump then binds 2 extracellular K+ ions. This causes the dephosphorylation of the pump, reverting it to its previous conformational state, transporting the K+ ions into the cell.
- The unphosphorylated form of the pump has a higher affinity for Na+ ions than K+ ions, so the two bound K+ ions are released. ATP binds, and the process starts again
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