Question

We need the assistance of enzymes such as choline acetyltransferase (ChAT) to make acetylcholine because there _____ a gene for acetylcholine. Neurons typically communicate with each other via _______ signals in the form of neurotransmitters like acetylcholine. We also need other enzymes to break down excess neurotransmitter. If we are exposed to acetylcholinesterase inhibitors, then we would expect to see a(n) _________ in the amount of acetylcholine available in the synaptic cleft.

A)Is not; electrical; decrease

B) Is; electrical; increase

C) Is not; chemical; increase

D) Is; chemical; decrease

Answer 1

The correct option is C) Is not; chemical; increase

Acetylcholine is synthesized by the enzyme choline acetyltransferase from choline and acetyl-CoA. Neurons communicate via both electrical signals and chemical signals. The electrical signals are action potentials and are used to propagate a signal within a neuron. Chemical signals are neurotransmitters which are used in interaction between neurons. Acetylcholinesterase is the enzyme used to break down acetylcholine into choline and acetate. An acetylcholinesterase inhibitor inhibits this enzyme and thereby increase both the level and duration of action of the neurotransmitter acetylcholine in the synaptic cleft.