You are looking at protein levels in a SERCA2a knock-out mouse. What would you expect to...

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You are looking at protein levels in a SERCA2a knock-out mouse. What would you expect to find in terms SERCA2a concentration

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Answer 1

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Knock-out mouse phase is very common in the experimental research in this type of mouse the specific target gene is removed for that reason it helps the researchers to understand how the gene has effect on the mice or the function of the gene.

If the mouse is SERCA2a knock-out which means the mouse genome or DNA does not contain the gene which codes for SERCA2a protein. So that the SERCA2a concentration will be low or may be possible that the mouse does not express that protein as the responsible gene is missing.

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