If the mutation is in isocitrate dehydrogenase, what would you expect to happen to the levels of : (increase/decrease)
isocitrate
a- ketoglutarate
glyoxylate
The main function of the Isocitrate dehydrogenase is to ctalyse the oxidative decarboxylation of isocitrate to -ketoglutarate.The mutation in isocitrate dehydrogenase arginine to histidine at 132(R132H) incrases the Affinity for -ketoglutarate.
If the mutation is in isocitrate dehydrogenase, what would you expect to happen to the levels...
would happen to the concentration of each of the following molecules: citrate, isocitrate, a-ketoglutarate, succinate, oxaloacetate, malonate, ADP, and ATP in the experiment if you treated these mitochondria with excess amounts of malonate?
What would you expect to happen to a newly synthesized soluble protein if a mutation caused the deletion of the KDEL sequence? a. The protein would be returned to the ER in COPI-coated vesicles. b. The protein will be carried forward through the Golgi apparatus. c. The protein will be trapped in COPII vesicles . d. The protein will be incorporated into COPI vesicles. e. The protein will be recognized by KDEL receptors and a retrieval sequence (KDEL sequence) will...
What citric acid cycle enzyme is not used in the glyoxylate cycle? A. malate dehydrogenase B. aconitase C. isocitrate dehydrogenase D. succinate dehyrogenase E. fumarase
What would be the effect of a mutation that enhances the activity of pyruvate dehydrogenase kinase? O There will be a buildup of lactate as the cells turn to fermentation for their energy requirements. O There will be an increase in fatty acid production as the concentration of acetyl CoA increases. O There will be an increase in the activity of the citric acid cycle with the increased production of acetyl CoA. The cell will begin to convert acetyl CoA...
11. What would happen in a liver cell if citrate levels were high? Tell me what pathways would increase and which would decrease. Mention at least three key regulatory enzymes that would be affected as a result of this increase in acetyl-CoA. (10 pts)
3. What would you expect to happen to the stock of domestic bonds in the hands of the public as R and Y both increase along a stable MM curve? Explain in intuitive terms how such a change in the stock of domestic bonds in the hands of the public could be brought about
a. What would happen if there was a mutation that caused APC to always be phosphorylated? (2 points).
Which one of the following conditions would increase the synthesis of fatty acids? a. A decrease in the insulin/glucagon ratio b. A decrease in the levels of cytosolic citrate c. An increase in the activity of the carnitine shuttle d. a decrease level of malonyl-SCoA e. A decreased activity of isocitrate dehydrogenase I keep researching this questions and end up with concluding that none of the choices are right. Please help thanks.
From an economist's viewpoint, what would you expect to happen in the market as the number of wireless providers goes from 2 to 8? Name and explain at least 3 things.
Part C Assume that you have a cylinder with a movable piston. What would happen to the gas volume of the cylinder if you were to decrease the pressure by 75% at constant T? The volume would decrease by 4 The volume would increase by 1 /4 The volume would decrease by 1/4 The volume would increase by 4 This is no volume change. Submit X Incorrect; Try Again; 5 attempts remaining Part D Assume that you have a cylinder...