Question

QUESTION 44 Which one of these statments is true? Amine hormones are small peptides made up of less than 200 amino acids Steroid hormones (such as testosterone) are water soluble for direct transport in blood Steroid hormones cannot diffuse through the nuclear membrane Steroid hormones bind to cytoplasmic or nuclear receptors and the complex acts as a transcription factor

Answer 1

Answer for question number 44 : The true statement among the following statements, the  option D (steroid hormones bind to cytoplasmic or nuclear receptors and the complex acts as transcription factor).

Explanation : Steroid hormones such as testoterone, estrogen etc., are hydrophobic in nature and can easily cross cytoplasmic as well as nuclear membranes. The receptors for steroid hormones are found in the cytoplasm and are referred to as intracellular or nuclear receptors. Once bound by the hormone in the cytoplasm, the hormone-receptor complex enters into the cytoplasm and binds to specific sequences on DNA called Hormone response elements (HREs) thus regulating the expression of genes at the level of transcription.