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QUESTION 17 Cytokines that play a role in the inflammatory response by enabling white blood cells to leave the blood vessels
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Question 17 Chemokines

Cells near the injury, releases a series of chemical signals which radiate from the site of inflammation. These signal proteins are called chemokines and their concentration is greatest in the area immediately surrounding the infection. The gradient of chemokine concentration provides an important road map for phagocytotic WBC including neutrophils as they make their way onto the scene. Following ever increasing chemokine concentration, phagocytes exit the leaky capillaries and enter the site of infection. Here they work engulfing and destroying the pathogens present. With the infection taken care of, the wound site begins to heal. After they engulf pathogen particles and eventually die these WBC eventually make up the pus that we associate with infected cuts and scrapes.

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