Many proteins, especially transcription factors, need to be delivered to the nucleus under certain cellular conditions...
Many proteins, especially transcription factors, need to be delivered to the nucleus under certain cellular conditions but not under others. How is it possible to control protein delivery to the nucleus? Discuss as many different mechanisms to regulate nuclear delivery as you can identify.
Homework Answers
The transcription factors are proteins that are synthesised in the cytoplasm. The transport of proteins from the cytoplasm to nucleus takes place through the nuclear import mechanism where the importin molecules and RanGTP tag along with the transcription factor and let it get imported into the nucleus. Other mechanism by which the protein import is regulated is by the GTP/GDP concentration in the cytoplasm that affects the RanGTP. These are the regulatory mechanisms by which protein transport occurs into the nucleus.
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