Which mutation has the most detrimental effect on the organism? Why?
wild type--> AUGAUUGUCCCCAAAUAG
Mutant 1 --> AUGAUUCUCCCCAAAUAG
Mutant 2 --> AUGAUUGUCCCCUAAUAG
Mutant 3--> AUGAUGUCCCCAAAUAG
The amino acid sequence of mRNA is found from the mRNA codon chart.
Please look in the image :
Mutant 1 is a mis-sense mutation. There are found single amino acid change. That's why it is not detrimental in nature
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Mutant 2 is a non sense mutation. But mutation is found at the last codon. UAA stops codon is created. The last amino acid is not found.
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Mutant 3 is a frame shift mutation. This leads to change the whole sequence of amino acid in a protein.
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Mutant 3 is more detrimental in nature. Because there found whole amino acid sequence change in the protein as compared to wild type.
Which mutation has the most detrimental effect on the organism? Why? wild type--> AUGAUUGUCCCCAAAUAG Mutant 1...
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