Question

Match: Diabetes Type I (IDDM) Lack of insulin produced [Choose) Insulin Acts to decrease blood sugar when levels are high Lack of insulin produced Glucagon Too much insulin produced Cells resistant to the insulin message Diabetes Type II (NIDDM) Acts to increase blood sugar levels when low Hypoglycemia [Choose)

Answer 1

ANSWER)

DIABETES TYPE I- LACK OF INSULIN PRODUCTION

INSULIN - ACT TO DECREASE BLOOD SUGAR WHEN LEVEL ARE HIGH

GLUCAGON- ACT TO INCREASE BLOOD SUGAR LEVEL WHEN LOW

DIABETES TYPE II- CELL RESISTANT TO INSULIN MESSSAGE

HYPOGLYCEMIA - TO MUCH INSULIN PRODUCE

EXPLANATION

PANCREASE IS A COMPOSITE GLAND WHICH ACT AS BOTH EXOCRINE AND ENDOCRINE GLAND. EXOCRINE CELL OF PANCREASE CONSIST OF CLUSTER OF CELL CALLED AS ACINI. THESE ACINI ARE SCATTERED THROUGHOUT PANCREASE FORMING CLUSTER KNOWN AS ISLET OF LANGERHANS. THE ISLET OF LANGHERHANS CONSIST OF 4 TYPE OF CELL

ALPHA CELL WHICH SECRETE GLUCAGON

BETA CELL WHICH SECRETE INSULIN

DELTA CELL WHICH SECRETE SOMATOSTATIN

F CELL WHICH SECRETE PANCREATIC POLYPEPTIDE

INSULIN AND GLUCAGON ARE ANTAGONIST TO EACH OTHER. GLUCAGON IS A LINEAR POLYPEPTIDE  CONSISTING OF 29 AMINOACID WHICH STIMULATE GLYCOGENOLYSIS THAT IS BREAKDOWN OF GLYCOGEN INTO GLUCOSE UNIT THUS INCREASING THE GLUCOSE LEVEL IN BLOOD. INSULIN IS POLYPEPTIDE THAT IS MADE UP OF TWO POLYPEPTIDE CHAIN - ALPHA AND BETA CHAIN WHICH IS 21 AMINO ACID AND 30 AMINO ACID LONG CHAIN RESPECTIVELY. INSULIN ACCELRATE THE TRANSPORT OF BLOOD SUGAR -GLUCOSE INTO THE CELL THUS DECREASING THE BLOOD SUGAR LEVEL .

TYPE I DIABETES - IS A TYPE OF DISORDER WHERE THE BETA CELL ARE UNABLE TO PRODUCE INSULIN THUS GLUCOSE LEVEL REMAIN HIGH IN THE BLOOD.

IN TYPE II DIABETES THE BODY IS ABLE TO FORM INSULIN BUT CELL BECOME RESISTANT TO INSULIN THAT IS CELL ARE UNABLE TO RESPOND TO INSULIN RESULTING LACK OF TRANSPORT OF BLOOD SUGAR TO CELL AND THUS THE BLOOD GLUCOSE LEVEL REMAIN HIGH

HYPOGLYCEMIA: IT IS A CONDITION WHERE THE BLOOD SUGAR LEVEL IS LOW. WHEN THERE WILL BE TOO MUCH INSULIN THEN THE HIGH AMOUNT OF GLUCOSE WILL BE TRANSPORTED TO THE CELL RESULTING TO THE CONDITION OF HYPOGLYCEMIA