What is the difference between antigenic drift and antigenic shift? Which of the two is the...
What is the difference between antigenic drift and antigenic shift? Which of the two is the reason annual influenza immunizations are necessary?
Give as complete an answer as possible for complete credit. You may write a paragraph, draw a diagram, make a PowerPoint slide, or a video. Feel free to be creative.
Homework Answers
Ans) Antigenic shift :
1. In this major changes takes place.
2. It gives rise to new subtype.
3. Involvement of one or two virus takes
place.
4. Passes from one species to other i.e. animal to
human.
5. Major changes takes place in the RNA
nucleotide.
6. Mutations are sudden as well as large.
7. It takes place only in the inflienza virus type
A.
8. It causes pandemics.
Antigenic drift :
1. Minor changes takes place.
2. Produces new strains of the virus.
3. Involvement of only one virus takes
place.
4. It takes place frequently.
5. Same species of organism are infected.
6. Small mutation in the RNA takes place.
7. Mutations are spontaneous as well as
random.
8. Due to presence of antibodies and drugs it is
easy to treat.
Antigenic drift needs annual inflienza immunization because of antigenic variations. The influenza virus mainly changes through drift. Antigenic drift means the accumalation of point mutations gradually in the yearly circulation of influenza as a result of high variation rates which are associated RNA dependent RNA polymerase at the time of replication of virus.
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