which of the following causes of mutation acts by creating double-strand breaks in DNA?
a) ionizing radiation
b) chemical pollutants
c) depurination
d) ultra-violet light
A) ionizing radiation
DNA double-strand breaks (DSBs) are viewed as the most cytotoxic sort of DNA injury. They can be presented by outside sources, for example, ionizing radiation (IR), by chemotherapeutic medications, for example, topoisomerase harms, Whenever left unrepaired, DSBs can cause cell demise.
which of the following causes of mutation acts by creating double-strand breaks in DNA? a) ionizing...
Ionizing radiation and oxidative damage can cause DNA double-strand breaks. A. True. B False Nucleotide Excision Repair involves recognition of distortions in the DNA double helix rather than specific base changes. A. True. B False Homologous recombination does not occur in prokaryotic cells. A. True. B False Many chemotherapeutic agents are paradoxically DNA damaging agents A. True. B False Meiot.c recombination starts with, double-strand break caused by errors In DNA replication A. True. B False ONA replication origins are typically...
Sort the following steps for repairing double-strand breaks by homologous recombination a) Ligation b) DNA synthesis using undamaged DNA as template c) DNA synthesis using original DNA as template d) Release of the invading strand e) Strand invasion f) Nuclease digestion (resection)
Which of the following is an example of a spontaneous mutation? Yeast DNA is exposed to acridine dye, resulting in distortion of the DNA double helix. Human cells are exposed to X-rays for a prolonged period of time, leading to multiple DNA strand breaks. DNA polymerase III accidently mismatches a G to a T during Escherichia coli DNA replication, resulting in a silent mutation. Plasmodium vivax cells are exposed to ultraviolet radiation, leading to the formation of thymine dimers within...
Which of the following is NOT a function of homologous recombination? Repair of DNA double strand breaks Repairing bulky DNA damage Pairing of homologous chromosomes in meiosis Rescue of collapsed replication forks
By definition, if the DNA of a cell undergoes a spontaneous mutation, is was NOT due to A.) Errors in DNA replication B.) Insertion of transposons C.) Exposure to radiation D.) Spontaneous depurination of nucleotides
1. A mutation in the gene for DNA ligase will impact which strand during DNA replication a. The leading b. The laggingc. Both the leading and the lagging d. Neither the leading strand or the lagging strand
48) If one strand of a DNA double helix ha one strand of a DNA double helix has the sequence AGTACTG, what will be the sequence of the other strand? A) GACGTCA B) AGTACTGC) GTCATGAD) TCATGAC 49) A DNA molecule has the sequence AGTTCAACT. The equivalent RNA molecule would have the sequence AGTTCAACT B) AGUUCAACU C) UGTTCUUCT D) UGUUCUUCU 50) what group(s) in amino acid carboxyl and Amino D) Hydroxyl and Carboxyl B) carbonyl and Amino C) Hydroxyl and Carbonyl
z Instructions Question 1 (Q039) In addition to the repair of DNA double-strand breaks, homologous recombination is a mechanism fe generating genetic diversity by swapping segments of parental chromosomes. During which process does swapping occur? DNA replication ODNA repair O meiosis transposition No new data to save. Last checked at 8:05am
*Template Strand of DNA 3. The following shows the first portion of a DNA strand of a gene that is 2,500 base pairs long. AUG TACȚTCCCGGAGCCC--- TAAG LLL ODRAL a. What is the amino acid sequence encoded for by this strand starting with the T nucleotide on the left? Met b. Give an example of a synonymous substitution (a silent mutation) that could occur in the second codon of the DNA strand. c. Give an example of a nonsense mutation...
The lagging strand in DNA replication?: (A) is synthesized after the leading strand. (B) causes the formation of Okazaki fragments in the leading strand. (C) is a consequence of replicating both strands of template DNA at a single replication fork. (D) requires its own replisome.