RNA processing is determined by phosphorylation patterns in the C-terminal repeat domain (CTD) of the RNA...
RNA processing is determined by phosphorylation patterns in the C-terminal repeat domain (CTD) of the RNA polymerase II. Explain in a mechanistic manner how a deficiency in the enzyme CTDK-1 affects RNA processing.
Homework Answers
There are many kinases in saccharomyces cerevisiae that phosphorylate the CTD of Rna polymerase II. CTD is essential and it has vital functions in initiation and elongation of transcription as well as in processing of MRna. The function of the CTD in these different processes appeares connected to phosphorylation of CTD, which changes through transcriptionery cycle. In saccharomyces cerevisiae, four enzymes are thre for CTD kinase activity. That os, Kin28- Ccl1, Srb10- Srb 11, CTDK-1, and Sgv1/Bur1 /Bur2. CTDK-1 is responsible for proper processing of a subset of yeast transcripts.
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RNA processing is determined by phosphorylation patterns in the
C-terminal repeat domain (CTD) of the RNA...
Describe how the carboxy terminal domain (CTD) of RNA polymerase II is involved in initiation and...
Describe how the carboxy terminal domain (CTD) of RNA polymerase II is involved in initiation and elongation of transcription. HTML Editori B I VA - A - Ix E 1 1 1 x X, DE T TH 12pt Paragraph Tube O words
Which of the following mRNA processing factors associates with the CTD of RNA polymerase II? A....
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Part A The sigma (?) subunit binds to the core RNA polymerase enzyme. The function of...
Part
A
The sigma (?) subunit binds to the core RNA polymerase
enzyme. The function of this sigma factor is to recognize and bind
to the promoter of a gene so that transcription can be initiated.
The closeup shows the secondary structure of the sigma (?)
subunit, which consists of four domains. Identify the domains
labeled 1-3.
The sigma (?) subunit binds to the core RNA polymerase
enzyme. The function of this sigma factor is to recognize and bind
to...
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How would you test the hypothesis that the C-terminal domain of a newly identified growth factor receptor is auto-inhibitory for receptor auto-phosphorylation in the absence of ligand?
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Describe how the carboxy terminal domain (CTD) of RNA polymerase II is involved in initiation and elongation of transcription. HTML Editori B I VA - A - Ix E 1 1 1 x X, DE T TH 12pt Paragraph Tube O words
Part
A
The sigma (?) subunit binds to the core RNA polymerase
enzyme. The function of this sigma factor is to recognize and bind
to the promoter of a gene so that transcription can be initiated.
The closeup shows the secondary structure of the sigma (?)
subunit, which consists of four domains. Identify the domains
labeled 1-3.
The sigma (?) subunit binds to the core RNA polymerase
enzyme. The function of this sigma factor is to recognize and bind
to...
How would you test the hypothesis that the C-terminal domain of a newly identified growth factor receptor is auto-inhibitory for receptor auto-phosphorylation in the absence of ligand?
(16 pts.) The gel shown below shows patterns observed for a STR (short tandem repeat) locus among four sets of parents (1-8) and four children (A-D). One child comes from each set of parents. 3. Why are there two bands for each parent? a. b. Although all the people shown here have two bands, it is possible (and not unusual) fora person to have only one band. Explain how this could happen. Consider earlier discussions on extensions to Mendelian genetics....
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Two identical twins who showed very similar methylation patterns when they were 4 years old show very divergent patterns at age 40. This divergence is most likely due to a different alternative splicing in the two individuals Ob different levels of histone acetyltransferase in the two individuals. Oc environmental differences that they experienced as adults. O d. different genomic imprinting in the two individuals. O e differences in their experiences in utero Suppose that a certain enzyme is synthesized whenever...
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