Homework Answers
Answer:
B. Activated by phosphorylation
Glycogen phosphorylase b (inactive form) is converted to active form by phosphorylation by the enzyme phosphorylase kinase.
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Glycogen phosphorylase is an enzyme important for breaking down glycogen. In response to epinephrine, glycogen phosphorylase...
8. The figure on the right is a glycogen phosphorylase (7 pts). Quo), (1) Two hormones...
8. The figure on the right is a glycogen phosphorylase (7 pts). Quo), (1) Two hormones regulate glycogen phosphorylase. Explain the effect of each hormone on this enzyme, especially for a) phosphorylation status (phosphorylated vs. non-phosphorylated), and b) the enzyme activity (activated vs. inactivated) of this enzyme (4 pts). Glucagon: Insulin: (2) Glycogen synthase is a processive enzyme. What may be the unique structural feature of glycogen synthase that makes it a processive enzyme? (3 pts)
Which statement is true? Epinephrine activates glycogen phosphorylase. Epinephrine increases glycolysis in muscle. Insulin decreases glycogen...
Which statement is true? Epinephrine activates glycogen phosphorylase. Epinephrine increases glycolysis in muscle. Insulin decreases glycogen breakdown by increasing phosphoprotein phosphatase-1 activity. All of the above
12. An enzyme, phosphodiesterase, catalyzes the conversion of CAMP to AMP. Using the glycogen control diagram...
12. An enzyme, phosphodiesterase, catalyzes the conversion of CAMP to AMP. Using the glycogen control diagram handed out separately, predict whether activating phosphodiesterase in turn activates or deactivates each of the enzymes below: Deactivates Activates Enzyme phosphorylase kinase glycogen phosphorylase phosphoprotein phosphatase-1 glycogen synthase ロロロロ ロロロロ Thus, when phosphodiesterase is activated, glycogen degradation is glycogen synthesis is activated Odeactivated and O activated Odeactivated. Based on your answers above, which hormone most likely activates phosphodiesterase? Check all that apply. O insulin...
1. Which of the following is true regarding glycogen metabolism? a. Glycogen synthase is activated by...
1. Which of the following is true regarding glycogen metabolism? a. Glycogen synthase is activated by phosporylation. b. Glycogen phosphorylase kinase activates glycogen phosphorylase through phosphorylation. c. The activation of PKA is downstream of insulin signaling in muscle cells. d. Glycogen phosphorylase releases free glucose from the ends of glycogen.
Which is not involved in the regulation of glycogen phosphorylase? A) Allosteric inhibition of phosphorylase by...
Which is not involved in the regulation of glycogen phosphorylase? A) Allosteric inhibition of phosphorylase by ATP B) Indirect, positive regulation by glucagon C) Phosphorylation of phosphorylase by protein kinase A (PKA) D) Direct and indirect regulation by protein phosphatase 1 (PP1) E) Indirect, negative regulation by protein phosphatase 2B (PP2B)
Q5. The phosphorylase enzyme, which is involved in breakdown of glycogen to glucose, is controlled by...
Q5. The phosphorylase enzyme, which is involved in breakdown of glycogen to glucose, is controlled by both allosteric mechanisms and posttranslational modification. A) Describe how the T to R transition and activity of glycogen phosphorylase would change under the following conditions: i) high AMP levels and activation of phosphoprotein phosphatase, ii) activation of phosphorylase kinase, ili) activation of phosphorylase kinase and high glucose levels. B) What properties would an uncompetitive inhibitor of glycogen phosphorylase have, what would the Lineweaver Burk...
Place in the right order the sequence of biochemical events between the release of epinephrine by...
Place in the right order the sequence of biochemical events between the release of epinephrine by the adrenal glands and the breakdown of glycogen in the liver. (1) Epinephrine is released by the adrenal glands. ( ) Activated beta-adrenergic receptors cause GTP for GDP exchange in the alpha subunits of Gs G proteins ( ) The activated catalytic subunits of PKA phosphorylate the inactive phosphorylase kinase b, activating it. ( ) Epinephrine travels in the bloodstream ( ) Two cAMP...
Protein kinase A phosphorylates _____, which then activates _____. A) phosphorylase kinase; glycogen phosphorylase B) protein...
Protein kinase A phosphorylates _____, which then activates _____. A) phosphorylase kinase; glycogen phosphorylase B) protein phosphatase 1; glycogen synthase C) glycogen phosphorylase; phosphoglucomutase D) adenylate cyclase; phosphorylase kinase
Which protein is regulated by phosphorylation? ect one: a. glycogen phosphorylase b. myoglobin C. collagen d....
Which protein is regulated by phosphorylation? ect one: a. glycogen phosphorylase b. myoglobin C. collagen d. All of the above. e. None of the above.
10.Which statement regarding the transcriptional regulation of PEP carboxykinase is false A. The promoter region of...
10.Which statement regarding the transcriptional regulation of PEP carboxykinase is false A. The promoter region of the PEP carboxykinase gene has binding sites for more than a dozen transcription factors B. Transcription and degradation are the primary means of regulating PEP carboxykinase gene C . A sterol regulatory binding element protein decrease expression of the PEP carboxykinase gene D. Insulin increase expression of the PEP carboxykinase gene 11. Glycogenesis - A. Occurs only in the liver and muscle B. Begins...
8. The figure on the right is a glycogen phosphorylase (7 pts). Quo), (1) Two hormones regulate glycogen phosphorylase. Explain the effect of each hormone on this enzyme, especially for a) phosphorylation status (phosphorylated vs. non-phosphorylated), and b) the enzyme activity (activated vs. inactivated) of this enzyme (4 pts). Glucagon: Insulin: (2) Glycogen synthase is a processive enzyme. What may be the unique structural feature of glycogen synthase that makes it a processive enzyme? (3 pts)
12. An enzyme, phosphodiesterase, catalyzes the conversion of CAMP to AMP. Using the glycogen control diagram handed out separately, predict whether activating phosphodiesterase in turn activates or deactivates each of the enzymes below: Deactivates Activates Enzyme phosphorylase kinase glycogen phosphorylase phosphoprotein phosphatase-1 glycogen synthase ロロロロ ロロロロ Thus, when phosphodiesterase is activated, glycogen degradation is glycogen synthesis is activated Odeactivated and O activated Odeactivated. Based on your answers above, which hormone most likely activates phosphodiesterase? Check all that apply. O insulin...
Q5. The phosphorylase enzyme, which is involved in breakdown of glycogen to glucose, is controlled by both allosteric mechanisms and posttranslational modification. A) Describe how the T to R transition and activity of glycogen phosphorylase would change under the following conditions: i) high AMP levels and activation of phosphoprotein phosphatase, ii) activation of phosphorylase kinase, ili) activation of phosphorylase kinase and high glucose levels. B) What properties would an uncompetitive inhibitor of glycogen phosphorylase have, what would the Lineweaver Burk...
Which protein is regulated by phosphorylation? ect one: a. glycogen phosphorylase b. myoglobin C. collagen d. All of the above. e. None of the above.
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