How do you calculate the net charge of a molecule? For example what would the net...
Homework Answers
Asp is the symbol for Aspartic acid.
Its structure is as shown.
The ionisation of -COOH group gives carboxylate ion and amino group is protonated to form ammonium ion.
Total net charge is -1. Hence, it is a negatively charged amino acid.
When pH is raised to 1.8, the carboxylate ions are protonated. This is because, pH 1.8 corresponds to highly acidic medium.
The net charge is +1.
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How
do you calculate the net charge of a molecule? For example what
would the net...
What is the approximate net charge of the following pentapeptide at pH 10? Arg-Gln-Cys-His-Ala What is...
What is the approximate net charge of the following pentapeptide at pH 10? Arg-Gln-Cys-His-Ala What is the Isoelectric point (pI) of the peptide given above? Use the pKa values given here when needed: Side group/ amino acid pKa Asp 3.9 Glu 4.1 HIs 6.0 Cys 8.4 Tyr 10.5 Lys 10.5 Arg 12.5 C-term 3.5 N-term 9.0
-2. Which of the following tripeptides would carry a net charge of-1 at pH 7? Markallthatapply....
-2. Which of the following tripeptides would carry a net charge of-1 at pH 7? Markallthatapply. (3 pts.) A. Asp-Ala-Arg C. Lys-Gly-Asn D. Glu-Lys-Asp E. Leu-Asp-Glu F. Arg-lleu-Cys B. Met-Pro-Glu The Kd for a dimeric protein complex is 2.2 μM. (3 pts.) Mark all that are true about this dimeric protein complex. A. 3. At equilibrium, the concentration of the individual subunits is very, very low. B. If this is a homodimer, it can be called an αβ dimer. C....
Hi. Please show work and I will gladly rate! 22. Calculate the net charge on the...
Hi. Please show work and I will gladly rate!
22. Calculate the net charge on the following peptide at pH 8. Arg-Glu-Gln-Asn-Asp-His-Lys-Arg-Glu-Asp
What about the pKa values of the R groups of the seven amino acids containing an...
What about the pKa values of the R groups of the seven amino acids containing an ionizable R group? Tyr 10.5 Lys 10.5 Arg 12.5 Asp 3.9 Glu 4.1 His 6.0 Cys 8.4 Indicate the approximate net charge of each of these seven R groups at pH 7.4. Indicate the approximate net charge of each of these seven amino acids at pH 7.4. Note: remember the carboxyl and the alpha-amino group in addition to the ionizable (acidic or basic) R...
19. Calculate the net charge on the following nonapeptide at the physiological pH 7.4, and predict...
19. Calculate the net charge on the following nonapeptide at the physiological pH 7.4, and predict the peptide's mobility in an electric field. Explain your answer. (4 pts) Gln-Tyr-Ala-Phe-Gly-Cys-Ser-His-Asp.
Using the pKa values given in the table on the right, determine the charge of the...
Using the pKa values given in the table on the right,
determine the charge of the side group of the following amino acids
at the pH specified. Consider the side group only (not including
the charges at the C–terminal or N– terminal).
2. Using the pka values given in the table on the right, determine the charge of the side group of the following amino acids at the pH specified. Consider the side group only (not including the charges at...
Can someone explain how these work? 4. For a solution of Cys (C), at what pH...
Can someone explain how these work?
4. For a solution of Cys (C), at what pH would the net charge be closest to 1? a) 10.7 b) 8.4 c) (1.9-8.4)/2 = 5.5 d) (10.7 + 8.4)/2 = 9.55 5. For a solution of Tyr (Y), what percentage of the side chain R group's OH would be deprotonated at pH = 10.5? a) 0% b) 25% c) 50% d) 100% 6. For the peptide His -Asp-Gln-Glu-Ala- Lys (HDQEAK), what would be...
I am trying to figure how to solve: "What is the total charge of an oligopeptide...
I am trying to figure how to solve: "What is the total charge of an oligopeptide with the sequence of Phe-Lys-Glu-Asp-Lys-Ala at pH 9.13?" The right answer appears to be: "50% with zero charge and 50% with a -1 charge" Can someone show me how to get to this answer?
What is meant when you say that two objects have like charges How do we tell...
What is meant when you say that two objects have like charges How do we tell that objects "like charges" How do we make objects with like charges Two objects are observed attract What do we know and what do we NOT know about them Your are given a piece of material. Propose an experiment or a series of experiments to determine if the material is a conductor or an insulator. State clearly what the outcome of each experiment will...
C,D, and E i need help with. 17. The following peptide forms part of Human Hemoglobin...
C,D, and E i need help with.
17. The following peptide forms part of Human Hemoglobin subunit gammaa Asp-Leu-Lys-Gly-Thr-Phe-Ala A) Which amino acids are likely to be on the side of peptid acids are likely to be on the side of peptide that faces the interior of the protein? Insert your answer leu, Gto.Pne, Ala B) Which are likely to be facing the aqueous environment? Insert your answer Asp, lys, Thr Draw the structure of the sequence at pH7.4. Using...
-2. Which of the following tripeptides would carry a net charge of-1 at pH 7? Markallthatapply. (3 pts.) A. Asp-Ala-Arg C. Lys-Gly-Asn D. Glu-Lys-Asp E. Leu-Asp-Glu F. Arg-lleu-Cys B. Met-Pro-Glu The Kd for a dimeric protein complex is 2.2 μM. (3 pts.) Mark all that are true about this dimeric protein complex. A. 3. At equilibrium, the concentration of the individual subunits is very, very low. B. If this is a homodimer, it can be called an αβ dimer. C....
Hi. Please show work and I will gladly rate!
22. Calculate the net charge on the following peptide at pH 8. Arg-Glu-Gln-Asn-Asp-His-Lys-Arg-Glu-Asp
19. Calculate the net charge on the following nonapeptide at the physiological pH 7.4, and predict the peptide's mobility in an electric field. Explain your answer. (4 pts) Gln-Tyr-Ala-Phe-Gly-Cys-Ser-His-Asp.
Using the pKa values given in the table on the right,
determine the charge of the side group of the following amino acids
at the pH specified. Consider the side group only (not including
the charges at the C–terminal or N– terminal).
2. Using the pka values given in the table on the right, determine the charge of the side group of the following amino acids at the pH specified. Consider the side group only (not including the charges at...
Can someone explain how these work?
4. For a solution of Cys (C), at what pH would the net charge be closest to 1? a) 10.7 b) 8.4 c) (1.9-8.4)/2 = 5.5 d) (10.7 + 8.4)/2 = 9.55 5. For a solution of Tyr (Y), what percentage of the side chain R group's OH would be deprotonated at pH = 10.5? a) 0% b) 25% c) 50% d) 100% 6. For the peptide His -Asp-Gln-Glu-Ala- Lys (HDQEAK), what would be...
What is meant when you say that two objects have like charges How do we tell that objects "like charges" How do we make objects with like charges Two objects are observed attract What do we know and what do we NOT know about them Your are given a piece of material. Propose an experiment or a series of experiments to determine if the material is a conductor or an insulator. State clearly what the outcome of each experiment will...
C,D, and E i need help with.
17. The following peptide forms part of Human Hemoglobin subunit gammaa Asp-Leu-Lys-Gly-Thr-Phe-Ala A) Which amino acids are likely to be on the side of peptid acids are likely to be on the side of peptide that faces the interior of the protein? Insert your answer leu, Gto.Pne, Ala B) Which are likely to be facing the aqueous environment? Insert your answer Asp, lys, Thr Draw the structure of the sequence at pH7.4. Using...
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