Question

Methionine is an amino acid made by E coli. The met (methionine) operon in E. coli...

Methionine is an amino acid made by E coli. The met (methionine) operon in E. coli responds to a repressor protein which itself is:

a. encoded by the operon

b. turned off when bound to methionine c. turned on when bound to methionine

d. unresponsive to any product of the methionine biosynthetic pathway

e. turned on when bound to tryptophan

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Answer #1

MetJ is a regulatory protein and when it combines with S-adenosylmethionine (i.e. SAM), it represses the expression of methionine operon and of enzymes involved in SAM synthesis. Met J itself is autoregulated. .i.e. by the presence of methionine

(b) i.e. turned off when bound to methionine

In place SAM Met can bind as in the following ref

http://pubs.rsc.org/en/content/articlehtml/2009/ob/b816495a

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