A tryptophan tRNA gene mutates so that it recognizes one of the three possible stop codons...
A tryptophan tRNA gene mutates so that it recognizes one of the three possible stop codons – TGA now codes for Trp, according to the mutant tRNA.
a) Will all proteins in the cell be affected by this mutation? Briefly explain your answer; if not all proteins will be affected, estimate about what fraction of proteins will be affected.
b) Gene X encodes the stop with TGA. How will this mutation affect the protein X that is produced?
c) Will all of the protein X produced in the cell be abnormal, or will only some of it be abnormal?
Homework Answers
A. No, not all proteins in the cell be affected by this
mutation. Because there are three stop codon present in the gene
UAA, UAG, UGA. In that only UGA is mutated and other 2 stop codons
are normal. So if some proteins has UAA, UAG they are not affected
by this mutation.
Due to three stop codon one is mutated by using equal probability
1/3 = 33% is mutated.
B. The mutated protein X has longer in length compare to normal protein X. There is no stop codon present in the mutated gene X the translation will continuous and add more amino acids than normal protein so it become non functional.
C. All of the protein X produced in the cell be abnormal.
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A tryptophan tRNA gene mutates so that it recognizes one of the
three possible stop codons...
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